Integration of transcriptomic and proteomic approaches for snake venom profiling

CM Modahl, AJ Saviola… - Expert Review of …, 2021 - Taylor & Francis
Introduction Snake venoms contain many protein and peptide isoforms with high levels of
sequence variation, even within a single species. Areas covered In this review, we highlight …

Snakes on a plain: biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake

CF Smith, ZL Nikolakis, K Ivey, BW Perry, DR Schield… - BMC biology, 2023 - Springer
Background Snake venoms are trophic adaptations that represent an ideal model to
examine the evolutionary factors that shape polymorphic traits under strong natural …

Modeling defensive functions of alkaloids within diverse chemical portfolios

J Yeager, PA Viteri Chancusi, Y Perez-Castillo… - Evolutionary …, 2024 - Springer
Studies of the evolution of anti-predatory phenotypes such as aposematic signals have
proven informative to demonstrate the role of selection on phenotypic divergence. Oophaga …

[HTML][HTML] Interpopulational variation and ontogenetic shift in the venom composition of Lataste's viper (Vipera latastei, Boscá 1878) from northern Portugal

I Avella, JJ Calvete, L Sanz, W Wüster, F Licata… - Journal of …, 2022 - Elsevier
Lataste's viper (Vipera latastei) is a venomous European viper endemic to the Iberian
Peninsula, recognised as medically important by the World Health Organization. To date, no …

Modern venomics—Current insights, novel methods, and future perspectives in biological and applied animal venom research

BM von Reumont, G Anderluh, A Antunes… - …, 2022 - academic.oup.com
Venoms have evolved> 100 times in all major animal groups, and their components, known
as toxins, have been fine-tuned over millions of years into highly effective biochemical …

A novel broad spectrum venom metalloproteinase autoinhibitor in the rattlesnake Crotalus atrox evolved via a shift in paralog function

FP Ukken, NL Dowell, M Hajra… - Proceedings of the …, 2022 - National Acad Sciences
The complexity of snake venom composition reflects adaptation to the diversity of prey and
may be driven at times by a coevolutionary arms race between snakes and venom-resistant …

The best of both worlds? Rattlesnake hybrid zones generate complex combinations of divergent venom phenotypes that retain high toxicity

CF Smith, ZL Nikolakis, BW Perry, DR Schield, JM Meik… - Biochimie, 2023 - Elsevier
Studying the consequences of hybridization between closely related species with divergent
traits can reveal patterns of evolution that shape and maintain extreme trophic adaptations …

A genome assembly for the southern Pacific rattlesnake, Crotalus oreganus helleri, in the western rattlesnake species complex

EP Westeen, M Escalona, ML Holding… - Journal of …, 2023 - academic.oup.com
Rattlesnakes play important roles in their ecosystems by regulating prey populations, are
involved in complex coevolutionary dynamics with their prey, and exhibit a variety of unusual …

Hunting behavior and feeding ecology of Mojave rattlesnakes (Crotalus scutulatus), prairie rattlesnakes (Crotalus viridis), and their hybrids in southwestern New …

DW Maag, YZ Francioli, N Shaw, AY Soni… - Ecology and …, 2023 - Wiley Online Library
Predators must contend with numerous challenges to successfully find and subjugate prey.
Complex traits related to hunting are partially controlled by a large number of co‐evolved …

Prey specificity of predatory venoms

O Michálek, GF King, S Pekár - Biological Reviews, 2024 - Wiley Online Library
Venom represents a key adaptation of many venomous predators, allowing them to
immobilise prey quickly through chemical rather than physical warfare. Evolutionary arms …