In-Line Aerosol therapy via nasal cannula during adult and paediatric normal, obstructive, and restrictive breathing
M Mac Giolla Eain, R MacLoughlin - Pharmaceutics, 2023 - mdpi.com
High-flow nasal oxygen therapy is being increasingly adopted in intensive and home care
settings. The concurrent delivery of aerosolised therapeutics allows for the targeted …
settings. The concurrent delivery of aerosolised therapeutics allows for the targeted …
Deposition of 11C-radiolabeled nicotine-containing aerosol in an airway cast model using positron emission tomography (PET)
JE Rose, AK Kuczaj, AG Mukhin, J Hoeng… - Aerosol Science and …, 2023 - Taylor & Francis
We recently developed an in vitro system for quantification of deposited mass of labeled
aerosol constituents in the human airway under realistic inhalation conditions including …
aerosol constituents in the human airway under realistic inhalation conditions including …
Evaluation of aerosol drug delivery with concurrent low-and high-flow nasal oxygen
B Murphy, MMG Eain, M Joyce, JB Fink… - ERJ open …, 2022 - Eur Respiratory Soc
Question addressed by study Administration of aerosol to patients receiving high-flow nasal
oxygen (HFNO) ranges from concurrent aerosol delivery by mouthpiece to aerosol via …
oxygen (HFNO) ranges from concurrent aerosol delivery by mouthpiece to aerosol via …
Aerosol Delivery Efficiency With High-Flow Nasal Cannula Therapy in Neonatal, Pediatric, and Adult Nasal Upper-Airway and Lung Models
RM DiBlasi, RJ Engberg, J Poli, KE Carlin… - Respiratory …, 2024 - liebertpub.com
BACKGROUND: High-flow nasal cannula (HFNC) systems employ different methods to
provide aerosol to patients. This study compared delivery efficiency, particle size, and …
provide aerosol to patients. This study compared delivery efficiency, particle size, and …
[HTML][HTML] Microfluidics produced ATRA-loaded PLGA NPs reduced tuberculosis burden in alveolar epithelial cells and enabled high delivered dose under simulated …
AZ Bahlool, B Cavanagh, A O'Sullivan… - European Journal of …, 2024 - Elsevier
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is second only to COVID-19 as
the top infectious disease killer worldwide. Multi-drug resistant TB (MDR-TB) may arise …
the top infectious disease killer worldwide. Multi-drug resistant TB (MDR-TB) may arise …
[HTML][HTML] Influence of mesh nebulizer characteristics on aerosol delivery in non-human primates
M Cabrera, D Le Pennec, S Le Guellec… - European Journal of …, 2023 - Elsevier
Abstract Non-Human Primates (NHPs) are particularly relevant for preclinical studies during
the development of inhaled biologics. However, aerosol inhalation in NHPs is difficult to …
the development of inhaled biologics. However, aerosol inhalation in NHPs is difficult to …
In vitro model for investigating aerosol dispersion in a simulated COVID-19 patient during high-flow nasal cannula treatment
JA McGrath, A O'Sullivan, M Joyce, MA Byrne… - Frontiers in …, 2022 - frontiersin.org
The use of high-flow nasal cannula in the treatment of COVID-19 infected patients has
proven to be a valuable treatment option to improve oxygenation. Early in the pandemic …
proven to be a valuable treatment option to improve oxygenation. Early in the pandemic …
Aerosol Delivery of a Novel Recombinant Modified Superoxide Dismutase Protein Reduces Oxidant Injury and Attenuates Escherichia coli Induced Lung Injury in …
SD McCarthy, MA Tilbury, CH Masterson… - Journal of Aerosol …, 2023 - liebertpub.com
Background: Acute respiratory distress syndrome (ARDS) is a life-threatening respiratory
failure syndrome with diverse etiologies characterized by increased permeability of alveolar …
failure syndrome with diverse etiologies characterized by increased permeability of alveolar …