Drawbacks of artificial intelligence and their potential solutions in the healthcare sector
Artificial intelligence (AI) has the potential to make substantial progress toward the goal of
making healthcare more personalized, predictive, preventative, and interactive. We believe …
making healthcare more personalized, predictive, preventative, and interactive. We believe …
Animal models and therapeutic molecular targets of cancer: utility and limitations
M Cekanova, K Rathore - Drug design, development and therapy, 2014 - Taylor & Francis
Cancer is the term used to describe over 100 diseases that share several common
hallmarks. Despite prevention, early detection, and novel therapies, cancer is still the …
hallmarks. Despite prevention, early detection, and novel therapies, cancer is still the …
[HTML][HTML] Re-evaluating the role of FOXOs in cancer
FOXO transcription factors are negatively regulated by the PI3K-PKB/AKT signaling pathway
and have been mainly considered to be tumor suppressors due to their inhibitory effect on …
and have been mainly considered to be tumor suppressors due to their inhibitory effect on …
SOX9 drives WNT pathway activation in prostate cancer
The transcription factor SOX9 is critical for prostate development, and dysregulation of SOX9
is implicated in prostate cancer (PCa). However, the SOX9-dependent genes and pathways …
is implicated in prostate cancer (PCa). However, the SOX9-dependent genes and pathways …
Development and characterisation of acquired radioresistant breast cancer cell lines
M Gray, AK Turnbull, C Ward, J Meehan… - Radiation …, 2019 - Springer
Background Radiotherapy plays an important role in the multimodal treatment of breast
cancer. The response of a breast tumour to radiation depends not only on its innate …
cancer. The response of a breast tumour to radiation depends not only on its innate …
Anti-estrogen treatment in endometrial cancer: a systematic review
WJ Van Weelden, LFAG Massuger, Enitec… - Frontiers in …, 2019 - frontiersin.org
Introduction: Hormonal therapy in endometrial cancer (EC) is used for patients who wish to
preserve fertility and for patients with advanced or recurrent disease in a palliative setting …
preserve fertility and for patients with advanced or recurrent disease in a palliative setting …
Genomic profiling of metastatic castration-resistant prostate cancer samples resistant to androgen receptor pathway inhibitors
N Menssouri, L Poiraudeau, C Helissey, L Bigot… - Clinical Cancer …, 2023 - AACR
Purpose: The androgen receptor axis inhibitors (ARPI; eg, enzalutamide, abiraterone
acetate) are administered in daily practice for men with metastatic castration-resistant …
acetate) are administered in daily practice for men with metastatic castration-resistant …
A microfluidic cancer-on-chip platform predicts drug response using organotypic tumor slice culture
S Chakrabarty, WF Quiros-Solano, MMP Kuijten… - Cancer research, 2022 - AACR
Optimal treatment of cancer requires diagnostic methods to facilitate therapy choice and
prevent ineffective treatments. Direct assessment of therapy response in viable tumor …
prevent ineffective treatments. Direct assessment of therapy response in viable tumor …
[HTML][HTML] Artificial intelligence in clinical health care applications
M Van Hartskamp, S Consoli, W Verhaegh… - Interactive journal of …, 2019 - i-jmr.org
The idea of artificial intelligence (AI) has a long history. It turned out, however, that reaching
intelligence at human levels is more complicated than originally anticipated. Currently, we …
intelligence at human levels is more complicated than originally anticipated. Currently, we …
Estrogen receptor pathway activity score to predict clinical response or resistance to neoadjuvant endocrine therapy in primary breast cancer
Endocrine therapy is important for management of patients with estrogen receptor (ER)–
positive breast cancer; however, positive ER staining does not reliably predict therapy …
positive breast cancer; however, positive ER staining does not reliably predict therapy …