Human tissues are composed of complex admixtures of different cell types and their
biologically meaningful analysis necessitates the procurement of pure samples of the cells …

Among human cutaneous malignancies, basal cell carcinoma is the most common. Solid
advances in unveiling the molecular mechanisms of basal cell carcinoma have emerged in …

Genomic analysis of archival tissues fixed in formalin is of fundamental importance in
biomedical research, and numerous studies have used such material. Although the …

Background Basal cell carcinoma (BCC) of the skin is the most common human cancer. The
genetic alterations underlying BCC development are only partly understood. Objectives To …

We describe a rapid noncontact method for the capture of single cells or small tissue areas
of any size or shape directly within the cap of a common microfuge tube. Prior to the laser …

DNA Microarrays Page 1 A MOLECULAR CLONING MANUAL DNA Microarrays EDITED
BY David Bowtell and Joseph Sambrook Page 2 Contents Vr 111 in 1 I The ih\'A …

Single-cell RNA sequencing (scRNA-seq) technology provides a powerful tool for
understanding complex biosystems at the single-cell and single-molecule level. The past …

Epidermal clones of p53-mutated keratinocytes are abundant in chronically sun-exposed
skin and may play an important role in early development of skin cancer. Advanced laser …

Carcinogenesis is a multi-step series of somatic genetic events. The complexity of this multi-
hit process makes it difficult to determine each single event and the definitive outcome of …

Background TheTP53gene has been shown to have an important role in the genesis of
sporadic, presumably mainly sunlight-related, basal cell carcinoma (BCC). However, its role …