Management of inflammatory bowel diseases in older adults

S Singh, BS Boland, T Jess, AA Moore - … Lancet Gastroenterology & …, 2023 - thelancet.com
The burden of inflammatory bowel disease (IBD) in older adults (ie, aged over 60 years old)
is increasing due to a combination of an ageing population with compounding prevalence of …

[HTML][HTML] Thiopurines: recent topics and their role in the treatment of inflammatory bowel diseases

K Tominaga, T Sugaya, T Tanaka… - Frontiers in …, 2021 - frontiersin.org
Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory bowel diseases
(IBD) of unknown etiology, characterized by repeated relapse and remission. The efficacy of …

Effectiveness and safety of vedolizumab in a matched cohort of elderly and nonelderly patients with inflammatory bowel disease: the IG‐IBD LIVE study

D Pugliese, G Privitera, F Crispino… - Alimentary …, 2022 - Wiley Online Library
Background Vedolizumab registration trials were the first to include elderly patients with
moderate‐to‐severe ulcerative colitis (UC) or Crohn's disease (CD), but few real‐life data …

Comorbidity, not patient age, is associated with impaired safety outcomes in vedolizumab‐and ustekinumab‐treated patients with inflammatory bowel disease—a …

VER Asscher, VBC Biemans, MJ Pierik… - Alimentary …, 2020 - Wiley Online Library
Background Few data are available on the effects of age and comorbidity on treatment
outcomes of vedolizumab and ustekinumab in inflammatory bowel disease (IBD). Aims To …

Thiopurines in Inflammatory Bowel Disease. How to optimize thiopurines in the biologic era?

CJ Gargallo-Puyuelo, V Laredo, F Gomollón - Frontiers in Medicine, 2021 - frontiersin.org
Thiopurines have been a cornerstone in the treatment of inflammatory bowel disease (IBD).
Although they have been used for more than 50 years, there are still some unsolved issues …

Ustekinumab and vedolizumab are equally safe and effective in elderly crohn's disease patients

GG Gebeyehu, J Fiske, E Liu, JK Limdi… - Digestive Diseases and …, 2023 - Springer
Background Anti-tumour necrosis factor (anti-TNF) agents are associated with increased
infection risk among elderly inflammatory bowel disease (IBD) patients, and thus, alternative …

Ulcerative colitis in adulthood and in older patients: same disease, same outcome, same risks?

W Fries, MG Demarzo, G Navarra, A Viola - Drugs & Aging, 2022 - Springer
The number of patients with inflammatory bowel disease (IBD) approaching an older age,
together with the number of over-60-year-old patients newly diagnosed with IBD, is steadily …

[HTML][HTML] The ENEIDA registry (Nationwide study on genetic and environmental determinants of inflammatory bowel disease) by GETECCU: Design, monitoring and …

Y Zabana, J Panés, P Nos, F Gomollón… - … y Hepatología (English …, 2020 - Elsevier
The ENEIDA registry, promoted by the Spanish Working Group on Crohn's Disease and
Ulcerative Colitis (GETECCU), was created in 2005 by a group of gastroenterologists …

Safety and effectiveness of ustekinumab in elderly Crohn's disease patients

J Fiske, E Liu, JK Limdi, TE Conley… - European journal of …, 2022 - ingentaconnect.com
Objective Anti-tumour necrosis factor (TNF) agents are associated with increased infection
risk among elderly IBD patients, but little is known about non anti-TNF biologics in this …

Disease-and treatment-related complications in older patients with inflammatory bowel diseases: comparison of adult-onset vs elderly-onset disease

JJ Rozich, J Luo, PS Dulai, AE Collins… - Inflammatory bowel …, 2021 - academic.oup.com
Background The incidence and prevalence of inflammatory bowel diseases (IBD) in older
adults are rising. There is a limited comparative assessment of risk of disease-and treatment …