Progress identifying and analyzing the human proteome: 2021 metrics from the HUPO human proteome project
The 2021 Metrics of the HUPO Human Proteome Project (HPP) show that protein expression
has now been credibly detected (neXtProt PE1 level) for 18 357 (92.8%) of the 19 778 …
has now been credibly detected (neXtProt PE1 level) for 18 357 (92.8%) of the 19 778 …
A multipathway phosphopeptide standard for rapid phosphoproteomics assay development
Recent advances in methodology have made phosphopeptide analysis a tractable problem
for many proteomics researchers. There are now a wide variety of robust and accessible …
for many proteomics researchers. There are now a wide variety of robust and accessible …
Improved protein and PTM characterization with a practical electron-based fragmentation on Q-TOF instruments
JS Beckman, VG Voinov, M Hare… - Journal of the …, 2021 - ACS Publications
Electron-based dissociation (ExD) produces uncluttered mass spectra of intact proteins
while preserving labile post-translational modifications. However, technical challenges have …
while preserving labile post-translational modifications. However, technical challenges have …
Mass spectrometry-based clinical proteomics–a revival
J Pauwels, K Gevaert - Expert Review of Proteomics, 2021 - Taylor & Francis
In clinical research, biomarkers can be defined as biomolecules that identify a specific
disease. The number of studies that use mass spectrometry (MS)-based proteomics for …
disease. The number of studies that use mass spectrometry (MS)-based proteomics for …
Profiling the human phosphoproteome to estimate the true extent of protein phosphorylation
Public phosphorylation databases such as PhosphoSitePlus (PSP) and PeptideAtlas (PA)
compile results from published papers or openly available mass spectrometry (MS) data …
compile results from published papers or openly available mass spectrometry (MS) data …
Deep-learning-derived evaluation metrics enable effective benchmarking of computational tools for phosphopeptide identification
Tandem mass spectrometry (MS/MS)-based phosphoproteomics is a powerful technology
for global phosphorylation analysis. However, applying four computational pipelines to a …
for global phosphorylation analysis. However, applying four computational pipelines to a …
SocioEconomicMag Meets a Platform for SES-Diverse College Students: A Case Study
Emerging research shows that individual differences in how people use technology
sometimes cluster by socioeconomic status (SES) and that when technology is not …
sometimes cluster by socioeconomic status (SES) and that when technology is not …
Revealing sequences and modifications of intact proteins using electron fragmentation
R Franklin - 2023 - ir.library.oregonstate.edu
People turn to mass spectrometry to answer some of life's most important questions. From
carbon dating of archeological finds to newborn blood screening tests, mass spectrometry …
carbon dating of archeological finds to newborn blood screening tests, mass spectrometry …
[HTML][HTML] Multi-laboratory experiment PME11 for the standardization of phosphoproteome analysis
N Colomé, J Abian, K Aloria, JM Arizmendi… - Journal of …, 2022 - Elsevier
Global analysis of protein phosphorylation by mass spectrometry proteomic techniques has
emerged in the last decades as a powerful tool in biological and biomedical research …
emerged in the last decades as a powerful tool in biological and biomedical research …
Profiling the Human Phosphoproteome to Estimate the True Extent of Protein Phosphorylation and Phosphosite Conservation
A Kalyuzhnyy - 2023 - search.proquest.com
Protein phosphorylation is a fundamental post-translation modification (PTM) that regulates
protein function and is well-studied in relation to cell signalling pathways and disease. The …
protein function and is well-studied in relation to cell signalling pathways and disease. The …