The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

Adiponectin is one of the most important adipocytokines secreted by adipocytes and is
called a “guardian angel adipocytokine” owing to its unique biological functions. Adiponectin …

Obesity is a major health problem strongly increasing the risk for various severe related
complications such as metabolic syndrome, cardiovascular diseases, respiratory disorders …

In this review, we focus on the secreted form of nicotinamide phosphoribosyltransferase
(NAMPT); extracellular NAMPT (eNAMPT), also known as pre‐B cell colony‐enhancing …

Nicotinamide phosphoribosyl-transferase (Nampt) or pre-B cell colony-enhancing factor or
visfatin represents a pleiotropic molecule acting as an enzyme, a cytokine and a growth …

The ghrelin system contains several components (eg, ghrelin with growing number of
alternative peptides, growth hormone secretagogue receptors (GHS-Rs), and ghrelin-O-acyl …

Objectives. Published data on resistin levels in patients with colorectal cancer (CRC) were
conflicting and heterogeneous. We conducted a meta‐analysis of observational studies to …

Obesity is demonstrated to be a risk factor in the development of cancers of various organs,
such as colon, prostate, pancreas and so on. Leptine (LEP) is the most renowned of the …

Purpose Equivocal results regarding the role of leptin in colorectal cancer (CRC) and
adenoma (CRA) have been reported. A case–control study investigating the association of …

Background Colorectal cancer (CRC) is a leading cause of cancer-related deaths globally.
The heterogeneity of the tumor microenvironment significantly influences patient prognosis …