Androgen deprivation therapy (ADT) has been the main management strategy for prostate
cancer for more than eight decades, nowadays achieved commonly by administration of …

The gut microbiota, a large ecosystem interacting with the host, has been shown to affect the
health and fitness of the host-microbial superorganism. Increasing evidence suggests that …

Inflammatory bowel disease (IBD), characterized by chronic inflammation of the
gastrointestinal tract, is a global health care problem. Compelling evidence shows sex …

Androgen deprivation therapy (ADT) is the main treatment strategy for men with metastatic
prostate cancer (PC). However, ADT is associated with various metabolic disturbances …

Background Androgen deprivation therapy (ADT) has been a mainstay of treatment for
advanced prostate cancer (PCa), but limited studies have been performed to investigate the …

Background Former cigarette smokers are at risk of developing ulcerative colitis (UC).
However, the impact of smoking behavior on the occurrence of UC according to the amount …

Objective To investigate the influences of inflammatory bowel disease (IBD), a rare but
morbid disease with increasing incidence, on prostate cancer management decisions. We …

Introduction A potential link exists between prostate cancer (PCa) disease and treatment
and increased inflammatory levels from gut dysbiosis. This study aims to examine if exercise …

The present study aimed to construct conditionally replicative adenovirus (CRAds) carrying
small hairpin (sh) RNA targeting enhancer of zeste homolog 2 (EZH2), in order to study its …

Methods We utilized two-sample Mendelian randomization (MR) to investigate the causal
relationship between testosterone and IBD among men using SNPs as genetic instrumental …