Transplantation is the only curative treatment for patients with kidney failure but it poses
unique immunological challenges that must be overcome to prevent allograft rejection and …

Cryptococcosis remains a significant opportunistic infection in solid organ transplant
recipients. Disease presentation and outcomes may be affected by, among other factors, the …

These updated guidelines from the Infectious Diseases Community of Practice of the
American Society of Transplantation review the diagnosis, prevention, and management of …

Tumor-specific T helper (Th) cells have a central role in the immune response against
cancer. However, there exist distinct Th cell subsets with very different and antagonizing …

Th1 and Th2 T helper cell subsets affect patterns of injury and outcomes in
glomerulonephritis. The recognition that human immune responses can be directed by two …

The identification of T‐helper 9 (Th9), Th17, Th22 cells as distinct subsets of CD 4+ T cells
has extended the Th1/Th2 paradigm in the adaptive immunity. In the past decade, many …

Host immunity is essential in facilitating the eradication of infection. However, immunological
recovery and an imbalance characterised by either suboptimum or excessive expression of …

Infiltration of renal allografts by leukocytes is a hallmark of acute transplant rejection.
Chemokines attract leukocytes bearing specific chemokine receptors, and the specific …

Non-HIV immunocompromised hosts develop immune reconstitution inflammatory syndrome
when the sudden change in the dominant T helper responses to inflammation is not well …

Hypothesis: Is renal allograft rejection initiated by the response to injury sustained during the
transplant process? Allograft rejection can be caused by numerous factors such as damage …