Salivary gland carcinoma: novel targets to overcome treatment resistance in advanced disease

L Di Villeneuve, IL Souza, FDS Tolentino… - Frontiers in …, 2020 - frontiersin.org
Salivary gland carcinomas (SGC) account for less than 5% of head and neck malignant
neoplasms, further subcategorized in over 20 histological subtypes. For the most part …

Diagnosis and management of malignant salivary gland tumors of the parotid gland

AG Lewis, T Tong, E Maghami - Otolaryngologic Clinics of North …, 2016 - oto.theclinics.com
Salivary gland cancers are rare with an annual incidence of approximately 3.0 cases per
100,000 in the United States accounting for less than 3% of all head and neck cancers. They …

Mucoepidermoid carcinoma. An update and review of the literature

A Peraza, R Gómez, J Beltran, FJ Amarista - Journal of stomatology, oral …, 2020 - Elsevier
Abstract Objective Mucoepidermoid Carcinoma (MEC) is the most common malignant
salivary gland neoplasm, representing 10 to 15% of all salivary neoplasms. A review of the …

Targeted therapy, chemotherapy, immunotherapy and novel treatment options for different subtypes of salivary gland cancer

SK Mueller, M Haderlein, S Lettmaier… - Journal of Clinical …, 2022 - mdpi.com
Surgical resection remains the first line treatment for salivary gland cancer (SGC). In the
case of locally advanced disease, surgery is followed by adjuvant radiotherapy. Surgical …

Salivary mucoepidermoid carcinoma revisited

A Coca-Pelaz, JP Rodrigo, A Triantafyllou… - European Archives of …, 2015 - Springer
Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid
carcinoma originating in salivary and salivary-type glands of the head and neck are …

Critical appraisal of histologic grading for mucoepidermoid carcinoma of salivary gland: is an objective prognostic 2-tiered grading system possible?

B Xu, B Alzumaili, KC Furlan, GH Martinez… - The American Journal …, 2023 - journals.lww.com
Multiple 3-tiered grading systems exist for mucoepidermoid carcinoma (MEC), leading to
controversial results on the frequency and prognostic values of each grade. We aimed to …

[HTML][HTML] Histopathologic, immunophenotypic and cytogenetic features of pulmonary mucoepidermoid carcinoma

AC Roden, JJ García, RN Wehrs, TV Colby, A Khoor… - Modern Pathology, 2014 - Elsevier
Pulmonary mucoepidermoid carcinoma is an uncommon but distinctive manifestation of
mucoepidermoid carcinoma. Pulmonary mucoepidermoid carcinoma occurs in adults and …

Advances and challenges in precision medicine in salivary gland cancer

G Lassche, W van Boxtel, MJL Ligtenberg… - Cancer treatment …, 2019 - Elsevier
Salivary gland cancer (SGC) is a rare malignancy consisting of 22 subtypes with different
genetic, histological and clinical characteristics. This rarity and heterogeneity makes …

Mucoacinar carcinoma: a rare variant of mucoepidermoid carcinoma

M Bundele, I Weinreb, B Xu, S Chiosea… - The American Journal …, 2021 - journals.lww.com
Mucoepidermoid carcinoma (MEC) is generally characterized by an admixture of mucous,
epidermoid and intermediate type cells. Numerous variants morphologies are described and …

[HTML][HTML] Comprehensive genomic profiling of salivary mucoepidermoid carcinomas reveals frequentBAP1, PIK3CA, and other actionable genomic alterations

K Wang, JD McDermott, AB Schrock, JA Elvin, L Gay… - Annals of …, 2017 - Elsevier
Background We sought to identify genomic alterations (GAs) in salivary mucoepidermoid
carcinomas. Patients and methods DNA was extracted from 48 mucoepidermoid …