BACKGROUND Antimicrobial peptides (AMPs) are small proteins with potent antibacterial,
antiviral, and antifungal activity. AMPs are ubiquitous among multicellular eukaryotes, with …

As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

Antimicrobial peptides (AMPs) are host-encoded antibiotics that combat invading
microorganisms. These short, cationic peptides have been implicated in many biological …

The membrane attack complex (MAC) is an important innate immune effector of the
complement terminal pathway that forms cytotoxic pores on the surface of microbes. Despite …

The impact of radiotherapy on the interaction between immune cells and cancer cells is
important not least because radiotherapy can be used alongside immunotherapy as a …

Perforin is a pore-forming protein that facilitates rapid killing of pathogen-infected or
cancerous cells by the immune system. Perforin is released from cytotoxic lymphocytes …

Abstract Pore Forming Toxins (PFTs) represent a key mechanism for permitting the passage
of proteins and small molecules across the lipid membrane. These proteins are typically …

Cell-based immunotherapy for the treatment of hematologic malignancies, such as leukemia
and lymphoma, has seen much success and played an increasingly important role in clinical …

Autophagy is an essential cellular homeostasis pathway initiated by multiple stimuli ranging
from nutrient deprivation to viral infection, playing a key role in human health and disease. At …

Granzyme B (GZMB) was first identified as a factor that could eliminate cells such as tumour
cells and bacteria/virus‐infected cells. However, comprehensive studies conducted on …