The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

The capsule of the fungal pathogen Cryptococcus neoformans

O Zaragoza, ML Rodrigues, M De Jesus… - Advances in applied …, 2009 - Elsevier
The capsule of the fungal pathogen Cryptococcus neoformans has been studied extensively
in recent decades and a large body of information is now available to the scientific …

Extracellular Vesicles Produced by Cryptococcus neoformans Contain Protein Components Associated with Virulence

ML Rodrigues, ES Nakayasu, DL Oliveira… - Eukaryotic …, 2008 - Am Soc Microbiol
Cryptococcus neoformans produces vesicles containing its major virulence factor, the
capsular polysaccharide glucuronoxylomannan (GXM). These vesicles cross the cell wall to …

The capsule of Cryptococcus neoformans

A Casadevall, C Coelho, RJB Cordero, Q Dragotakes… - Virulence, 2019 - Taylor & Francis
The capsule of Cryptococcus neoformans is its dominant virulence factor and plays a key
role in the biology of this fungus. In this essay, we focus on the capsule as a cellular …

Vesicular Polysaccharide Export in Cryptococcus neoformans Is a Eukaryotic Solution to the Problem of Fungal Trans-Cell Wall Transport

ML Rodrigues, L Nimrichter, DL Oliveira, S Frases… - Eukaryotic …, 2007 - Am Soc Microbiol
The mechanisms by which macromolecules are transported through the cell wall of fungi are
not known. A central question in the biology of Cryptococcus neoformans, the causative …

Fungal cell gigantism during mammalian infection

O Zaragoza, R García-Rodas, JD Nosanchuk… - PLoS …, 2010 - journals.plos.org
The interaction between fungal pathogens with the host frequently results in morphological
changes, such as hyphae formation. The encapsulated pathogenic fungus Cryptococcus …

Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival

O Zaragoza, CJ Chrisman, MV Castelli… - Cellular …, 2008 - Wiley Online Library
Cryptococcus neoformans is a facultative intracellular pathogen. The most distinctive feature
of C. neoformans is a polysaccharide capsule that enlarges depending on environmental …

How Sweet it is! Cell Wall Biogenesis and Polysaccharide Capsule Formation in Cryptococcus neoformans

TL Doering - Annual review of microbiology, 2009 - annualreviews.org
Cryptococcus neoformans is a pathogenic fungus responsible for severe opportunistic
infections. The most prominent feature of this yeast is its elaborate polysaccharide capsule …

Cryptococcus neoformans can form titan-like cells in vitro in response to multiple signals

N Trevijano-Contador, HC de Oliveira… - PLoS …, 2018 - journals.plos.org
Cryptococcus neoformans is an encapsulated pathogenic yeast that can change the size of
the cells during infection. In particular, this process can occur by enlarging the size of the …

Sec6‐dependent sorting of fungal extracellular exosomes and laccase of Cryptococcus neoformans

J Panepinto, K Komperda, S Frases… - Molecular …, 2009 - Wiley Online Library
The cell wall of pathogenic fungi such as Cryptococcus neoformans, provides a formidable
barrier to secrete virulence factors that produce host cell damage. To study secretion of …