Autism spectrum disorders and the gastrointestinal tract: insights into mechanisms and clinical relevance

LY Hung, KG Margolis - Nature Reviews Gastroenterology & …, 2024 - nature.com
Autism spectrum disorders (ASDs) are recognized as central neurodevelopmental disorders
diagnosed by impairments in social interactions, communication and repetitive behaviours …

[HTML][HTML] Gut microbiota profiles in children and adolescents with psychiatric disorders

M Soltysova, A Tomova, D Ostatnikova - Microorganisms, 2022 - mdpi.com
The aim of our work is to summarize the current state of knowledge on gut microbiota
differences in children and adolescents with psychiatric disorders. To find the relevant …

[HTML][HTML] Ketogenic diet ameliorates autism spectrum disorders-like behaviors via reduced inflammatory factors and microbiota remodeling in BTBR T+ Itpr3tf/J mice

I Olivito, E Avolio, D Minervini, T Soda, C Rocca… - Experimental …, 2023 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is increasing, but its complete etiology is still
lacking. Recently, application of ketogenic diet (KD) has shown to reduce abnormal …

[HTML][HTML] Microbial glutamate metabolism predicts intravenous cocaine self-administration in diversity outbred mice

TDB Tran, H Nguyen, E Sodergren, PE Dickson… - …, 2023 - Elsevier
The gut microbiome is thought to play a critical role in the onset and development of
psychiatric disorders, including depression and substance use disorder (SUD). To test the …

[HTML][HTML] Nutritional intervention as a complementary neuroprotective approach against propionic acid-induced neurotoxicity and associated biochemical autistic …

SRM Alsubaiei, HA Alfawaz, RS Bhat, A El-Ansary - Metabolites, 2023 - mdpi.com
Since there is no known cure for autism spectrum disorder (ASD), its incidence rate is on the
rise. Common comorbidities like gastrointestinal problems are observed as common signs of …

[HTML][HTML] The Dose–Response Effect of Fluoride Exposure on the Gut Microbiome and Its Functional Pathways in Rats

Z Mo, J Wang, X Meng, A Li, Z Li, W Que, T Wang… - Metabolites, 2023 - mdpi.com
Metabolic activities within the gut microbiome are intimately linked to human health and
disease, especially within the context of environmental exposure and its potential …

[HTML][HTML] Gut microbiota and risk of polycystic ovary syndrome: Insights from Mendelian randomization

J Li, Y Chen, Y Zhang, L Zeng, K Li, B Xie, S Luo, J Gao - Heliyon, 2023 - cell.com
Background Polycystic ovary syndrome (PCOS) is a multifaceted endocrine and metabolic
syndrome with complex origins and pathogenesis that has not yet been fully elucidated …

[HTML][HTML] Issues for patchy tissues: Defining roles for gut-associated lymphoid tissue in neurodevelopment and disease

T Abo-Shaban, SS Sharna, S Hosie, CYQ Lee… - Journal of Neural …, 2023 - Springer
Individuals diagnosed with neurodevelopmental conditions such as autism spectrum
disorder (ASD; autism) often experience tissue inflammation as well as gastrointestinal …

[HTML][HTML] Gut Microbiota Ecological and Functional Modulation in Post-Stroke Recovery Patients: An Italian Study

R Marsiglia, C Marangelo, P Vernocchi, M Scanu… - Microorganisms, 2023 - mdpi.com
Ischemic stroke (IS) can be caused by perturbations of the gut–brain axis. An imbalance in
the gut microbiota (GM), or dysbiosis, may be linked to several IS risk factors and can …

[HTML][HTML] Seizure susceptibility to various convulsant stimuli in the BTBR mouse model of autism spectrum disorders

M Tallarico, A Leo, E Russo, R Citraro… - Frontiers in …, 2023 - frontiersin.org
Background: Autism spectrum disorders (ASDs) are one of the most severe chronic
childhood disorders in terms of prevalence, morbidity, and impact on society. Interestingly …