Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Translation of aptamers toward clinical diagnosis and commercialization

S Liu, Y Xu, X Jiang, H Tan, B Ying - Biosensors and Bioelectronics, 2022 - Elsevier
The dominance of antibodies in diagnostics has gradually changed following the discovery
of aptamers in the early 1990s. Aptamers offer inherent advantages over traditional …

A novel colorimetric aptasensor for ultrasensitive detection of aflatoxin M1 based on the combination of CRISPR-Cas12a, rolling circle amplification and catalytic …

K Abnous, NM Danesh, M Ramezani, M Alibolandi… - Analytica Chimica …, 2021 - Elsevier
Colorimetric approaches have received noticeable attention among sensing methods in
view of simplicity and watching the color change of sample by the naked eyes. However …

A Y-shape-structured electrochemiluminescence biosensor based on carbon quantum dots and locked nucleic acid probe for microRNA determination with single …

Y Zhong, LX Huang, MT Lin, ZY Zhang, AL Liu… - Biosensors and …, 2023 - Elsevier
Since microRNAs (miRNAs) are predictors of tumorigenesis, accurate identification and
quantification of miRNAs with highly similar sequences are expected to reflect tumor …

Recent progress of biosensors for the detection of lung cancer markers

S Chen, M Li, T Weng, D Wang, J Geng - Journal of Materials …, 2023 - pubs.rsc.org
Lung cancer is one of the most common cancers worldwide and the leading cause of death.
Early screening of lung cancer is exceptionally essential for later treatment. Abnormal lung …

Circulating tumor cells in cancer diagnostics and prognostics by single-molecule and single-cell characterization

T Chowdhury, B Cressiot, C Parisi, G Smolyakov… - ACS …, 2023 - ACS Publications
Circulating tumor cells (CTCs) represent an interesting source of biomarkers for diagnosis,
prognosis, and the prediction of cancer recurrence, yet while they are extensively studied in …

Vertically ordered mesoporous silica film-assisted electrochemical cytosensor for the sensitive detection of HeLa cells

Z Zeng, Y Zhao, L Yang, F Xi, D Su - Frontiers in Chemistry, 2023 - frontiersin.org
Designing fast and simple quantitative methods on cheap and disposable electrodes for the
early detection of HeLa cells is highly desirable for clinical diagnostics and public health. In …

The Dual-Response–Single-Amplification Fluorescent Nanomachine for Tumor Imaging and Gastric Cancer Diagnosis

P Zhang, Y Tong, X Huang, Y Chen, Y Li, D Luan, J Li… - ACS …, 2023 - ACS Publications
Gastric cancer (GC) is one of the most common tumors worldwide and is the leading cause
of tumor-related mortality. Traditional biomarkers and screening methods cannot meet the …

Detection of circulating tumor cells: Advances and critical concerns

X Hu, X Zang, Y Lv - Oncology Letters, 2021 - spandidos-publications.com
Metastasis is the main cause of cancer‑related death and the major challenge in cancer
treatment. Cancer cells in circulation are termed circulating tumor cells (CTCs). Primary …

Ultrasensitive detection of 17β-estradiol (E2) based on multistep isothermal amplification

W Wang, Y Peng, J Wu, M Zhang, Q Li, Z Zhao… - Analytical …, 2021 - ACS Publications
17β-Estradiol (E2) can cause an adverse effect on the human endocrine system even at the
nanomolar level. Measurements of very low levels of E2 remain a critical challenge due to …