The persistent deterioration of our environmental assets has initiated 'a push'among the
scientific community for increased reliance on eco-friendly methodologies minimizing the …

Chalcones are α, β unsaturated aromatic ketones having enone moiety and exhibit a wide
array of pharmaceutical and biological activities. Chalcones possess a wide range of …

A series of molecular hybrids based on pyrazoline and 1, 2, 3-triazole pharmacophores
were designed and synthesized as antidiabetic agents. The structures of all the derivatives …

Spirocyclic oxindoles and triazolyl derivatives posses remarkable biological activities. In
present work, we have described an efficient one pot four-component domino reaction of 1 …

Multicomponent reactions, conducted in a domino, sequential or consecutive fashion, have
not only considerably enhanced synthetic efficiency as one-pot methodology, but they have …

Oxo-hexahydroquinoline (5-oxo-HHQ) represents a biologically attractive fused heterocyclic
core. Various synthetic analogs of 5-oxo-HHQ have been synthesized and assessed for …

Multicomponent reactions (MCRs) have inherent advantages in pot, atom, and step
economy (PASE). This important green synthetic approach has gained increasing attention …

In this work, we have developed green and efficient regioselective and chemoselective
syntheses of 5‐aryloyl‐1, 3‐dimethyl‐7‐thioxo‐5, 6, 7, 8‐tetrahydropyrimido [4, 5‐d] …

A series of novel molecular hybrids containing pyrazole, pyridinone and 1, 2, 3-triazoles
have been synthesized by one-pot four-component reaction of Meldrum's acid, substituted …

Due to the notable therapeutic importance of 1, 4-disubstituted-1, 2, 3-triazoles linked with
amine and ester groups, a series of 1, 2, 3-triazole hybrid containing amine-ester …