Bone development and healing processes involve a complex cascade of biological events
requiring well-orchestrated synergism with bone cells, growth factors, and other trophic …

Tea, Camellia sinensis, which belongs to the family Theaceae, is a shrub or evergreen tree
up to 16 m in height. Green tea is very popular because of its marked health benefits …

The natural dietary product tea (Camellia sinensis) and its bioactive polyphenols such as
epigallocatechin gallate (EGCG) and theaflavin (TF) demonstrated potential anticancer …

The protease enzyme, matrix metalloproteinase-2 (MMP-2) has been a target of choice for
the drug development due to its multi-façade involvement in numerous diseased conditions …

Background: The antioxidant properties of epigallocatechin-gallate (EGCG), a green tea
compound, have been already studied in various diseases. Improving the bioavailability of …

Evidence for demonstrating the role of the green tea component epigallocatechin-3-gallate
(EGCG) in esophageal squamous cell carcinoma cells is limited. In this study, we …

The extracellular matrix (ECM) is a highly dynamic network constantly remodeled by a fine-
tuned protein formation and degradation balance. Matrix metalloproteinases (MMPs) …

Hepatocellular carcinoma (HCC), one of the most notorious malignancies globally, has a
high fatality and poor prognosis. Though remarkable breakthroughs have been made in the …

Non-genetic MMP-2 insufficiency is a relatively unexplored condition which could be
induced by pathological overexpression of endogenous MMP-2 inhibitors such as TIMPs …

Myocardial infarction is a worldwide disease with high morbidity and mortality and a major
cause of chronic heart failure, seriously affecting patients' quality of life. Natural medicine …