Nicotinic acetylcholine receptors (nAChRs) are integral membrane proteins and prototypic
members of the ligand‐gated ion‐channel superfamily, which has precursors in the …

Autoantibodies against three different postsynaptic antigens and one presynaptic antigen at
the neuromuscular junction are known to cause myasthenic syndromes. The mechanisms by …

Mutations in GFPT1 underlie a congenital myasthenic syndrome (CMS) characterized by a
limb-girdle pattern of muscle weakness. Glutamine-fructose-6-phosphate transaminase 1 …

Abstract Autoimmune Autonomic Ganglionopathy (AAG) is a rare immune-mediated disease
of the autonomic nervous system. The incidence of AAG is unknown and diagnosis is often …

Myasthenia gravis (MG) with antibodies against the acetylcholine receptor (AChR–MG) is
considered as a prototypic autoimmune disease. The thymus is important in the …

Myasthenia gravis (MG) is usually caused by autoantibodies against muscle nicotinic
acetylcholine receptor (AChR), which is composed of five subunits (α2βγδ or α2βɛδ) …

The electron diffraction structure of nicotinic acetylcholine receptor (nAChR) from Torpedo
marmorata and the X-ray crystallographic structure of acetylcholine binding protein (AChBP) …

Myasthenia gravis (MG) is usually caused by autoantibodies against the human muscle
acetylcholine receptor (AChR). Plasmapheresis offers a therapeutic option, but, as well as …

Myasthenia gravis (MG), a prototypic antibody-mediated autoimmune disease, presents an
excellent target for scientific research aimed at a better understanding of the disease itself …

Myasthenia gravis (MG) is an autoimmune disorder caused by autoantibodies targeting
components of the postsynaptic membrane of the neuromuscular junction (NMJ), leading to …