A molecular view of DNA flexibility
DNA dynamics can only be understood by taking into account its complex mechanical
behavior at different length scales. At the micrometer level, the mechanical properties of …
behavior at different length scales. At the micrometer level, the mechanical properties of …
[HTML][HTML] A suite of tutorials for the WESTPA rare-events sampling software [Article v1. 0]
The weighted ensemble (WE) strategy has been demonstrated to be highly efficient in
generating pathways and rate constants for rare events such as protein folding and protein …
generating pathways and rate constants for rare events such as protein folding and protein …
AMOEBA polarizable atomic multipole force field for nucleic acids
The AMOEBA polarizable atomic multipole force field for nucleic acids is presented. Valence
and electrostatic parameters were determined from high-level quantum mechanical data …
and electrostatic parameters were determined from high-level quantum mechanical data …
Competition between chiral solvents and chiral monomers in the helical bias of supramolecular polymers
ML Ślęczkowski, MFJ Mabesoone, P Ślęczkowski… - Nature Chemistry, 2021 - nature.com
Solute–solvent interactions are key for the assembly and proper functioning of
biomacromolecules and play important roles in many fields of organic and polymer …
biomacromolecules and play important roles in many fields of organic and polymer …
Non-canonical DNA structures in the human ribosomal DNA
E Smirnov, P Molínová, N Chmúrčiaková… - Histochemistry and Cell …, 2023 - Springer
Non-canonical structures (NCS) refer to the various forms of DNA that differ from the B-
conformation described by Watson and Crick. It has been found that these structures are …
conformation described by Watson and Crick. It has been found that these structures are …
Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity
CRISPR (clustered regularly interspaced short palindromic repeat) endonucleases are at
the forefront of biotechnology, synthetic biology and gene editing. Methods for controlling …
the forefront of biotechnology, synthetic biology and gene editing. Methods for controlling …
Emerging biomimetic applications of DNA nanotechnology
H Shen, Y Wang, J Wang, Z Li… - ACS applied materials & …, 2018 - ACS Publications
Re-engineering cellular components and biological processes has received great interest
and promised compelling advantages in applications ranging from basic cell biology to …
and promised compelling advantages in applications ranging from basic cell biology to …
Chimeric guides probe and enhance Cas9 biochemical activity
DNA substitutions in RNA can probe the importance of A-form structure, 2′-hydroxyl
contacts, and conformational constraints within RNA-guided enzymes. Using this approach …
contacts, and conformational constraints within RNA-guided enzymes. Using this approach …
Computational study of the role of counterions and solvent dielectric in determining the conductance of B-DNA
DNA naturally exists in a solvent environment, comprising water and salt molecules such as
sodium, potassium, magnesium, etc. Along with the sequence, the solvent conditions …
sodium, potassium, magnesium, etc. Along with the sequence, the solvent conditions …
Screening of structural and functional alterations in duckweed (Lemna minor) induced by per-and polyfluoroalkyl substances (PFASs) with FTIR spectroscopy
YL Wu, Q Xiong, B Wang, YS Liu, PL Zhou, LX Hu… - Environmental …, 2023 - Elsevier
As a class of common emerging pollutants, per-and polyfluoroalkyl substances (PFASs) and
their alternatives have been widely detected in various environmental matrices, exhibiting a …
their alternatives have been widely detected in various environmental matrices, exhibiting a …