Inductively coupled plasma mass spectrometry

T Van Acker, S Theiner, E Bolea-Fernandez… - Nature Reviews …, 2023 - nature.com
Inductively coupled plasma mass spectrometry (ICP-MS) combines plasma chemistry, which
produces singly charged elemental ions, with mass spectrometric detection. Unlike other …

Laser ablation–inductively coupled plasma–mass spectrometry imaging in biology

PA Doble, RG de Vega, DP Bishop, DJ Hare… - Chemical …, 2021 - ACS Publications
Elemental imaging gives insight into the fundamental chemical makeup of living organisms.
Every cell on Earth is comprised of a complex and dynamic mixture of the chemical elements …

SEAM is a spatial single nuclear metabolomics method for dissecting tissue microenvironment

Z Yuan, Q Zhou, L Cai, L Pan, W Sun, S Qumu, S Yu… - Nature …, 2021 - nature.com
Spatial metabolomics can reveal intercellular heterogeneity and tissue organization. Here
we report on the spatial single nuclear metabolomics (SEAM) method, a flexible platform …

Neurotoxicity linked to dysfunctional metal ion homeostasis and xenobiotic metal exposure: redox signaling and oxidative stress

C Garza-Lombó, Y Posadas, L Quintanar… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Essential metals such as copper, iron, manganese, and zinc play a role as
cofactors in the activity of a wide range of processes involved in cellular homeostasis and …

Recent advances in quantitative LA-ICP-MS analysis: challenges and solutions in the life sciences and environmental chemistry

A Limbeck, P Galler, M Bonta, G Bauer… - Analytical and …, 2015 - Springer
Laser ablation–inductively coupled plasma–mass spectrometry (LA-ICP-MS) is a widely
accepted method for direct sampling of solid materials for trace elemental analysis. The …

Bioimaging mass spectrometry of trace elements–recent advance and applications of LA-ICP-MS: a review

JS Becker, A Matusch, B Wu - Analytica chimica acta, 2014 - Elsevier
Bioimaging using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)
offers the capability to quantify trace elements and isotopes within tissue sections with a …

Review of the applications of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) to the analysis of biological samples

D Pozebon, GL Scheffler, VL Dressler… - Journal of Analytical …, 2014 - pubs.rsc.org
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has received
significant attention over the last 10 years and has been widely used for the analysis of …

Recent developments in the design of rapid response cells for laser ablation-inductively coupled plasma-mass spectrometry and their impact on bioimaging …

SJM Van Malderen, AJ Managh, BL Sharp… - Journal of Analytical …, 2016 - pubs.rsc.org
This review covers developments in the design of Laser Ablation (LA) cells, the associated
transport tubing assembly, and their coupling to Inductively Coupled Plasma-Mass …

A brief history of brain iron accumulation in Parkinson disease and related disorders

PB Foley, DJ Hare, KL Double - Journal of Neural Transmission, 2022 - Springer
Iron has a long and storied history in Parkinson disease and related disorders. This
essential micronutrient is critical for normal brain function, but abnormal brain iron …

Imaging metals in biology: balancing sensitivity, selectivity and spatial resolution

DJ Hare, EJ New, MD de Jonge… - Chemical Society Reviews, 2015 - pubs.rsc.org
Metal biochemistry drives a diverse range of cellular processes associated with
development, health and disease. Determining metal distribution, concentration and flux …