Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors

KL Pennington, MM DeAngelis - Eye and vision, 2016 - Springer
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
adults over 50 years old. Genetic, epidemiological, and molecular studies are beginning to …

Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease

PS Bernstein, B Li, PP Vachali, A Gorusupudi… - Progress in retinal and …, 2016 - Elsevier
The human macula uniquely concentrates three carotenoids: lutein, zeaxanthin, and meso-
zeaxanthin. Lutein and zeaxanthin must be obtained from dietary sources such as green …

Age-related macular degeneration preferred practice pattern®

CJ Flaxel, RA Adelman, ST Bailey, A Fawzi, JI Lim… - …, 2020 - aaojournal.org
Background: Age-related macular degeneration is a leading cause of severe, irreversible
vision impairment in developed countries. The primary risk factors for the development of …

Critical review: vegetables and fruit in the prevention of chronic diseases

H Boeing, A Bechthold, A Bub, S Ellinger… - European journal of …, 2012 - Springer
Background Vegetables and fruit provide a significant part of human nutrition, as they are
important sources of nutrients, dietary fibre, and phytochemicals. However, it is uncertain …

Role of lutein and zeaxanthin in visual and cognitive function throughout the lifespan

EJ Johnson - Nutrition reviews, 2014 - academic.oup.com
The relationship between lutein and zeaxanthin and visual and cognitive health throughout
the lifespan is compelling. There is a variety of evidence to support a role for lutein and …

Lutein and zeaxanthin—Food sources, bioavailability and dietary variety in age-related macular degeneration protection

B Eisenhauer, S Natoli, G Liew, VM Flood - Nutrients, 2017 - mdpi.com
Lutein and zeaxanthin (L/Z) are the predominant carotenoids which accumulate in the retina
of the eye. The impact of L/Z intake on the risk and progression of age-related macular …

Age‐related macular degeneration: new paradigms for treatment and management of AMD

LF Hernández-Zimbrón… - Oxidative medicine …, 2018 - Wiley Online Library
Age‐related macular degeneration (AMD) is a well‐characterized and extensively studied
disease. It is currently considered the leading cause of visual disability among patients over …

Dietary nutrient intake and progression to late age-related macular degeneration in the age-related eye disease studies 1 and 2

E Agrón, J Mares, TE Clemons, A Swaroop, EY Chew… - Ophthalmology, 2021 - Elsevier
Purpose To analyze associations between the dietary intake of multiple nutrients and risk of
progression to late age-related macular degeneration (AMD), its subtypes, and large drusen …

Lutein+ zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial

Age-Related Eye Disease Study 2 (AREDS2) … - Jama, 2013 - jamanetwork.com
Importance Oral supplementation with the Age-Related Eye Disease Study (AREDS)
formulation (antioxidant vitamins C and E, beta carotene, and zinc) has been shown to …

Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No. 3

EY Chew, TE Clemons, JP SanGiovanni… - JAMA …, 2014 - jamanetwork.com
Importance The Age-Related Eye Disease Study (AREDS) formulation for the treatment of
age-related macular degeneration (AMD) contains vitamin C, vitamin E, beta carotene, and …