Harnessing transition metal scaffolds for targeted antibacterial therapy

C Weng, YLK Tan, WG Koh… - Angewandte Chemie …, 2023 - Wiley Online Library
Antimicrobial resistance, caused by persistent adaptation and growing resistance of
pathogenic bacteria to overprescribed antibiotics, poses one of the most serious and urgent …

Ruthenium complexes in the fight against pathogenic microorganisms. An extensive review

AC Munteanu, V Uivarosi - Pharmaceutics, 2021 - mdpi.com
The widespread use of antibiotics has resulted in the emergence of drug-resistant
populations of microorganisms. Clearly, one can see the need to develop new, more …

'Carbon-monoxide-releasing molecule-2 (CORM-2)'is a misnomer: ruthenium toxicity, not CO release, accounts for its antimicrobial effects

HM Southam, MP Williamson, JA Chapman, RL Lyon… - Antioxidants, 2021 - mdpi.com
Carbon monoxide (CO)-releasing molecules (CORMs) are used to deliver CO, a biological
'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and …

Advances and prospects in metabolic engineering of Escherichia coli for L-tryptophan production

S Liu, JZ Xu, WG Zhang - World Journal of Microbiology and …, 2022 - Springer
As an important raw material for pharmaceutical, food and feed industry, highly efficient
production of L-tryptophan by Escherichia coli has attracted a considerable attention …

Ruthenium (II) carbon monoxide releasing molecules: Structural perspective, antimicrobial and anti-inflammatory properties

AM Mansour, RM Khaled, E Khaled, SK Ahmed… - Biochemical …, 2022 - Elsevier
Carbon monoxide has recently emerged to promote tissue regeneration, enhance the innate
immune system, and have anti-inflammatory and antibacterial properties. While the first …

Hydrogen sulfide and carbon monoxide tolerance in bacteria

SS Mendes, V Miranda, LM Saraiva - Antioxidants, 2021 - mdpi.com
Hydrogen sulfide and carbon monoxide share the ability to be beneficial or harmful
molecules depending on the concentrations to which organisms are exposed. Interestingly …

Anaerobic and hydrogenogenic carbon monoxide-oxidizing prokaryotes: Versatile microbial conversion of a toxic gas into an available energy

Y Fukuyama, M Inoue, K Omae, T Yoshida… - Advances in applied …, 2020 - Elsevier
Carbon monoxide (CO) is a gas that is toxic to various organisms including humans and
even microbes; however, it has low redox potential, which can fuel certain microbes, namely …

A comprehensive review and comparison of L-tryptophan biosynthesis in Saccharomyces cerevisiae and Escherichia coli

X Ren, Y Wei, H Zhao, J Shao, F Zeng… - … in Bioengineering and …, 2023 - frontiersin.org
L-tryptophan and its derivatives are widely used in the chemical, pharmaceutical, food, and
feed industries. Microbial fermentation is the most commonly used method to produce L …

Metabolic adaptations of Escherichia coli to extended zinc exposure: insights into tricarboxylic acid cycle and trehalose synthesis

M Rihacek, L Kosaristanova, T Fialova, T Rypar… - BMC microbiology, 2024 - Springer
Balanced bacterial metabolism is essential for cell homeostasis and growth and can be
impacted by various stress factors. In particular, bacteria exposed to metals, including the …

Metal-based carbon monoxide releasing molecules with promising cytotoxic properties

AM Mansour, RM Khaled, G Ferraro, OR Shehab… - Dalton …, 2024 - pubs.rsc.org
Carbon monoxide, the “silent killer” gas, is increasingly recognised as an important
signalling molecule in human physiology, which has beneficial biological properties. A …