Obesity is a global pandemic associated with macro-and microvascular endothelial
dysfunction. Microvascular endothelial dysfunction has recently emerged as a significant risk …

Vascular cognitive impairment (VCI) refers to all forms of cognitive disorder related to
cerebrovascular diseases, including vascular mild cognitive impairment, post-stroke …

Importance Preclinical and clinical studies have suggested a neuroprotective effect of
remote ischemic conditioning (RIC), which involves repeated occlusion/release cycles on …

Background Intracranial atherosclerotic stenosis (ICAS) is one of the most common causes
of stroke worldwide, and it is associated with a high risk of recurrent stroke with currently …

Chronic cerebral hypoperfusion is associated with vascular dementia (VaD). Cerebral
hypoperfusion may initiate complex molecular and cellular inflammatory pathways that …

Smith and Markus Cerebral Small Vessel Disease Trials 39 dysmetabolism, and glucose
dysregulation that are the primary targets for current ischemic stroke prevention. As an …

Oligovascular coupling contributes to white matter vascular homeostasis. However, little is
known about the effects of oligovascular interaction on oligodendrocyte precursor cell (OPC) …

Objective We conducted a post hoc exploratory analysis of Remote Ischemic Conditioning
for Acute Moderate Ischemic Stroke (RICAMIS) to determine whether early remote ischemic …

Spontaneous intracerebral hemorrhage (ICH) produces the highest acute mortality and
worst outcomes of all stroke subtypes. Hematoma volume is an independent determinant of …

Despite decades of formidable exploration, multi-organ ischemia-reperfusion injury (IRI)
encountered, particularly amongst elderly patients with clinical scenarios, such as age …