Mitochondria not only supply the energy for cell function, but also take part in cell signaling.
This review describes the dysfunctions of mitochondria in aging and neurodegenerative …

Patients with peripheral artery disease have a marked reduction in exercise performance
and daily ambulatory activity irrespective of their limb symptoms of classic or atypical …

Aminoglycosides exhibit ototoxicity by damaging mitochondria, which in turn generate
reactive oxygen species that induce hair cell death and subsequent hearing loss. It is well …

In most cases, the death of neurons in certain parts of the brain is the defining feature of a
condition that is classified as neurodegenerative. There have been studies conducted on …

Ischemic stroke is a clinically common cerebrovascular disease whose main risks include
necrosis, apoptosis and cerebral infarction, all caused by cerebral ischemia and reperfusion …

Mitochondria play an essential role in cell survival by providing energy, calcium buffering,
and regulating apoptosis. A growing body of evidence shows that mitochondrial dysfunction …

COVID-19 is a severe respiratory infection caused by coronavirus 2.(SARS-CoV-2). Even
while SARS-CoV-2 predominantly affects the respiratory system, it can cause problems for …

Background Spinal muscular atrophy (SMA) is a progressive motor neuron disease causing
loss of motor function and reduced life expectancy, for which limited treatment is available …

Parkinson's disease (PD) is one of the most common neurodegenerative disorders. The
exact causes of neuronal damage are unknown, but mounting evidence indicates that …

Nucleic acid autoantibodies, increase type I interferon (IFN-α) levels, and immune cell
hyperactivation are hallmarks of systemic lupus erythematosus (SLE). Notably, immune cell …