Animal models of traumatic brain injury

Y Xiong, A Mahmood, M Chopp - Nature Reviews Neuroscience, 2013 - nature.com
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity both in civilian life
and on the battlefield worldwide. Survivors of TBI frequently experience long-term disabling …

Mechanics of the brain: perspectives, challenges, and opportunities

A Goriely, MGD Geers, GA Holzapfel… - … and modeling in …, 2015 - Springer
The human brain is the continuous subject of extensive investigation aimed at
understanding its behavior and function. Despite a clear evidence that mechanical factors …

The mechanics of traumatic brain injury: a review of what we know and what we need to know for reducing its societal burden

DF Meaney, B Morrison… - Journal of …, 2014 - asmedigitalcollection.asme.org
Traumatic brain injury (TBI) is a significant public health problem, on pace to become the
third leading cause of death worldwide by 2020. Moreover, emerging evidence linking …

Traumatic brain injury: an overview of pathobiology with emphasis on military populations

I Cernak, LJ Noble-Haeusslein - Journal of Cerebral Blood …, 2010 - journals.sagepub.com
This review considers the pathobiology of non-impact blast-induced neurotrauma (BINT).
The pathobiology of traumatic brain injury (TBI) has been historically studied in experimental …

Mechanisms of primary blast-induced traumatic brain injury: insights from shock-wave research

A Nakagawa, GT Manley, AD Gean, K Ohtani… - Journal of …, 2011 - liebertpub.com
Traumatic brain injury caused by explosive or blast events is traditionally divided into four
phases: primary, secondary, tertiary, and quaternary blast injury. These phases of blast …

Blast-related traumatic brain injury

JV Rosenfeld, AC McFarlane, P Bragge… - The Lancet …, 2013 - thelancet.com
A bomb blast may cause the full severity range of traumatic brain injury (TBI), from mild
concussion to severe, penetrating injury. The pathophysiology of blast-related TBI is …

Brain injuries from blast

CR Bass, MB Panzer, KA Rafaels, G Wood… - Annals of biomedical …, 2012 - Springer
Traumatic brain injury (TBI) from blast produces a number of conundrums. This review
focuses on five fundamental questions including:(1) What are the physical correlates for …

Animal models of traumatic brain injury

VE Johnson, DF Meaney, DK Cullen… - Handbook of clinical …, 2015 - Elsevier
Traumatic brain injury (TBI) is a major health issue comprising a heterogeneous and
complex array of pathologies. Over the last several decades, numerous animal models have …

Blast-induced mild traumatic brain injury

GA Elder, EM Mitsis, ST Ahlers, A Cristian - Psychiatric Clinics, 2010 - psych.theclinics.com
Traumatic brain injury (TBI) has been a major cause of mortality and morbidity in the wars in
Iraq and Afghanistan, known as Operation Iraqi Freedom (OIF) and Operation Enduring …

MicroRNA let-7i is a promising serum biomarker for blast-induced traumatic brain injury

N Balakathiresan, M Bhomia, R Chandran… - Journal of …, 2012 - liebertpub.com
Blast-induced traumatic brain injury (TBI) is of significant concern in soldiers returning from
the current conflicts in Iraq and Afghanistan. Incidents of TBI have increased significantly in …