The basal ganglia and the cerebellum: nodes in an integrated network

AC Bostan, PL Strick - Nature Reviews Neuroscience, 2018 - nature.com
The basal ganglia and the cerebellum are considered to be distinct subcortical systems that
perform unique functional operations. The outputs of the basal ganglia and the cerebellum …

Cerebral plasticity: Windows of opportunity in the developing brain

FY Ismail, A Fatemi, MV Johnston - European journal of paediatric …, 2017 - Elsevier
Background Neuroplasticity refers to the inherently dynamic biological capacity of the central
nervous system (CNS) to undergo maturation, change structurally and functionally in …

[HTML][HTML] The anatomical basis for dystonia: the motor network model

HA Jinnah, V Neychev, EJ Hess - Tremor and other hyperkinetic …, 2017 - ncbi.nlm.nih.gov
Background The dystonias include a clinically and etiologically very diverse group of
disorders. There are both degenerative and non-degenerative subtypes resulting from …

Current opinions and areas of consensus on the role of the cerebellum in dystonia

VG Shakkottai, A Batla, K Bhatia, WT Dauer, C Dresel… - The Cerebellum, 2017 - Springer
A role for the cerebellum in causing ataxia, a disorder characterized by uncoordinated
movement, is widely accepted. Recent work has suggested that alterations in activity …

The non-motor syndrome of primary dystonia: clinical and pathophysiological implications

M Stamelou, MJ Edwards, M Hallett, KP Bhatia - Brain, 2012 - academic.oup.com
Dystonia is typically considered a movement disorder characterized by motor
manifestations, primarily involuntary muscle contractions causing twisting movements and …

New roles for the cerebellum in health and disease

SL Reeber, TS Otis, RV Sillitoe - Frontiers in systems neuroscience, 2013 - frontiersin.org
The cerebellum has a well-established role in maintaining motor coordination and studies of
cerebellar learning suggest that it does this by recognizing neural patterns, which it uses to …

Imaging insights into basal ganglia function, Parkinson's disease, and dystonia

AJ Stoessl, S Lehericy, AP Strafella - The Lancet, 2014 - thelancet.com
Recent advances in structural and functional imaging have greatly improved our ability to
assess normal functions of the basal ganglia, diagnose parkinsonian syndromes …

The anatomical basis of dystonia: current view using neuroimaging

S Lehéricy, MAJ Tijssen, M Vidailhet, R Kaji… - Movement …, 2013 - Wiley Online Library
This review will consider the knowledge that neuroimaging studies have provided to the
understanding of the anatomy of dystonia. Major advances have occurred in the use of …

[HTML][HTML] Deep brain stimulation for movement disorders of basal ganglia origin: restoring function or functionality?

T Wichmann, MR DeLong - Neurotherapeutics, 2016 - Elsevier
Deep brain stimulation (DBS) is highly effective for both hypo-and hyperkinetic movement
disorders of basal ganglia origin. The clinical use of DBS is, in part, empiric, based on the …

Striatal cholinergic dysfunction as a unifying theme in the pathophysiology of dystonia

KLE Jaunarajs, P Bonsi, MF Chesselet… - Progress in …, 2015 - Elsevier
Dystonia is a movement disorder of both genetic and non-genetic causes, which typically
results in twisted posturing due to abnormal muscle contraction. Evidence from dystonia …