Neuroimaging biomarkers in schizophrenia

NV Kraguljac, WM McDonald… - American Journal of …, 2021 - Am Psychiatric Assoc
Schizophrenia is a complex neuropsychiatric syndrome with a heterogeneous genetic,
neurobiological, and phenotypic profile. Currently, no objective biological measures—that is …

[HTML][HTML] NODDI in clinical research

K Kamiya, M Hori, S Aoki - Journal of neuroscience methods, 2020 - Elsevier
Diffusion MRI (dMRI) has proven to be a useful imaging approach for both clinical diagnosis
and research investigating the microstructures of nervous tissues, and it has helped us to …

MR biomarkers of degenerative brain disorders derived from diffusion imaging

C Andica, K Kamagata, T Hatano… - Journal of Magnetic …, 2020 - Wiley Online Library
The incidence of neurodegenerative diseases has shown an increasing trend. These
conditions typically cause progressive functional disability. Identification of robust …

Could psychedelic drugs have a role in the treatment of schizophrenia? Rationale and strategy for safe implementation

G Wolf, S Singh, K Blakolmer, L Lerer, T Lifschytz… - Molecular …, 2023 - nature.com
Schizophrenia is a widespread psychiatric disorder that affects 0.5–1.0% of the world's
population and induces significant, long-term disability that exacts high personal and …

[HTML][HTML] Neurite orientation dispersion and density imaging in psychiatric disorders: a systematic literature review and a technical note

NV Kraguljac, M Guerreri, MJ Strickland… - … Psychiatry Global Open …, 2023 - Elsevier
While major psychiatric disorders lack signature diagnostic neuropathologies akin to
dementias, classic postmortem studies have established microstructural involvement, ie …

[HTML][HTML] Transdiagnostic in vivo magnetic resonance imaging markers of neuroinflammation

LKL Oestreich, MJ O'Sullivan - Biological Psychiatry: Cognitive …, 2022 - Elsevier
Accumulating evidence suggests that inflammation is not limited to archetypal inflammatory
diseases such as multiple sclerosis, but instead represents an intrinsic feature of many …

Neurite orientation dispersion and density imaging reveals white matter microstructural alterations in adults with autism

C Andica, K Kamagata, E Kirino, W Uchida, R Irie… - Molecular Autism, 2021 - Springer
Background Evidences suggesting the association between behavioral anomalies in autism
and white matter (WM) microstructural alterations are increasing. Diffusion tensor imaging …

In vivo imaging of gray matter microstructure in major psychiatric disorders: opportunities for clinical translation

A Nazeri, C Schifani, JAE Anderson, SH Ameis… - Biological Psychiatry …, 2020 - Elsevier
Postmortem studies reveal that individuals with major neuropsychiatric disorders such as
schizophrenia and autism spectrum disorder have gray matter microstructural abnormalities …

White matter integrity, duration of untreated psychosis, and antipsychotic treatment response in medication-naïve first-episode psychosis patients

NV Kraguljac, T Anthony, CJ Morgan, RD Jindal… - Molecular …, 2021 - nature.com
It is becoming increasingly clear that longer duration of untreated psychosis (DUP) is
associated with adverse clinical outcomes in patients with psychosis spectrum disorders …

[HTML][HTML] Microstructural white matter abnormalities in multiple sclerosis and neuromyelitis optica spectrum disorders: Evaluation by advanced diffusion imaging

S Kato, A Hagiwara, K Yokoyama, C Andica… - Journal of the …, 2022 - Elsevier
Introduction Despite differences in the pathogenesis and treatment of multiple sclerosis (MS)
and neuromyelitis optica spectrum disorders (NMOSD), it remains difficult to distinguish …