MST-m6A: A Novel Multi-Scale Transformer-based Framework for Accurate Prediction of m6A Modification Sites Across Diverse Cellular Contexts
Abstract N6-methyladenosine (m6A) modification, a prevalent epigenetic mark in eukaryotic
cells, is crucial in regulating gene expression and RNA metabolism. Accurately identifying …
cells, is crucial in regulating gene expression and RNA metabolism. Accurately identifying …
iACP-DFSRA: Identification of Anticancer Peptides Based on a Dual-channel Fusion Strategy of ResCNN and Attention
X Wang, Z Zhang, C Liu - Journal of Molecular Biology, 2024 - Elsevier
Anticancer peptides (ACPs) have been widely applied in the treatment of cancer owing to
good safety, rational side effects, and high selectivity. However, the number of ACPs that …
good safety, rational side effects, and high selectivity. However, the number of ACPs that …
DOGpred: A Novel Deep Learning Framework for Accurate Identification of Human O-linked Threonine Glycosylation Sites
KW Lee, NT Pham, HJ Min, HW Park, JW Lee… - Journal of Molecular …, 2025 - Elsevier
O-linked glycosylation is a crucial post-transcriptional modification that regulates protein
function and biological processes. Dysregulation of this process is associated with various …
function and biological processes. Dysregulation of this process is associated with various …
Discovery of anticancer peptides from natural and generated sequences using deep learning
J Yue, T Li, J Xu, Z Chen, Y Li, S Liang, Z Liu… - International Journal of …, 2025 - Elsevier
Anticancer peptides (ACPs) demonstrate significant potential in clinical cancer treatment
due to their ability to selectively target and kill cancer cells. In recent years, numerous …
due to their ability to selectively target and kill cancer cells. In recent years, numerous …
[HTML][HTML] Antimicrobial Peptide with a Bent Helix Motif Identified in Parasitic Flatworm Mesocestoides corti
The urgent need for antibiotic alternatives has driven the search for antimicrobial peptides
(AMPs) from many different sources, yet parasite-derived AMPs remain underexplored. In …
(AMPs) from many different sources, yet parasite-derived AMPs remain underexplored. In …
[HTML][HTML] Role of Peptide Associations in Enhancing the Antimicrobial Activity of Adepantins: Comparative Molecular Dynamics Simulations and Design Assessments
Adepantins are peptides designed to optimize antimicrobial biological activity through the
choice of specific amino acid residues, resulting in helical and amphipathic structures. This …
choice of specific amino acid residues, resulting in helical and amphipathic structures. This …
Anticancer Peptides Classification Using Long-Short-Term Memory with Novel Feature Representation
Cancer treatment is a challenging endeavor because of the intricacy, heterogeneity, and
diversity of cancer causes. Comprehensive therapeutic approaches are crucial for cancer …
diversity of cancer causes. Comprehensive therapeutic approaches are crucial for cancer …