Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Enhancing in situ cancer vaccines using delivery technologies

N Gong, MG Alameh, R El-Mayta, L Xue… - Nature Reviews Drug …, 2024 - nature.com
In situ cancer vaccination refers to any approach that exploits tumour antigens available at a
tumour site to induce tumour-specific adaptive immune responses. These approaches hold …

Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery

N Boehnke, JP Straehla, HC Safford, M Kocak… - Science, 2022 - science.org
To accelerate the translation of cancer nanomedicine, we used an integrated genomic
approach to improve our understanding of the cellular processes that govern nanoparticle …

Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation

H Li, Q Luo, H Zhang, X Ma, Z Gu, Q Gong… - Chemical Society …, 2023 - pubs.rsc.org
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …

Anti-tumor immune potentiation targets-engineered nanobiotechnologies: design principles and applications

R Jiao, X Lin, Q Zhang, Y Zhang, W Qin, Q Yang… - Progress in Materials …, 2024 - Elsevier
Combined therapeutic strategies hold promises in augmenting antigen release to enhance
anti-tumor immunity, which have garnered attention in numerous scholarly reviews. Beyond …

[HTML][HTML] Carrier-free highly drug-loaded biomimetic nanosuspensions encapsulated by cancer cell membrane based on homology and active targeting for the …

Y Fan, Y Cui, W Hao, M Chen, Q Liu, Y Wang, M Yang… - Bioactive materials, 2021 - Elsevier
Nanosuspensions, as a new drug delivery system for insoluble drugs, are only composed of
a drug and a small amount of stabilizer, which is dispersed in an aqueous solution with high …

Designing drug delivery systems for cell therapy

LLW Wang, Y Gao, Z Feng, DJ Mooney… - Nature Reviews …, 2024 - nature.com
Cell therapies, such as immune cell and stem cell therapies, are being preclinically and
clinically explored for the treatment of various diseases, but are often limited by low efficacy …

Stiffness of targeted layer-by-layer nanoparticles impacts elimination half-life, tumor accumulation, and tumor penetration

SM Kong, DF Costa, A Jagielska… - Proceedings of the …, 2021 - National Acad Sciences
Nanoparticle (NP) stiffness has been shown to significantly impact circulation time and
biodistribution in anticancer drug delivery. In particular, the relationship between particle …

Nanomedicine strategies for heating “cold” ovarian cancer (OC): next evolution in immunotherapy of OC

Y Yang, T Zhao, Q Chen, Y Li, Z Xiao… - Advanced …, 2022 - Wiley Online Library
Immunotherapy has revolutionized cancer treatment, dramatically improving survival rates of
melanoma and lung cancer patients. Nevertheless, immunotherapy is almost ineffective …

Dynamic light scattering distributions by any means

N Farkas, JA Kramar - Journal of Nanoparticle Research, 2021 - Springer
Dynamic light scattering (DLS) is an essential technique for nanoparticle size analysis and
has been employed extensively for decades, but despite its long history and popularity, the …