The genetic basis of major depressive disorder
J Flint - Molecular psychiatry, 2023 - nature.com
The genetic dissection of major depressive disorder (MDD) ranks as one of the success
stories of psychiatric genetics, with genome-wide association studies (GWAS) identifying …
stories of psychiatric genetics, with genome-wide association studies (GWAS) identifying …
Could polygenic risk scores be useful in psychiatry?: a review
Importance Polygenic risk scores (PRS) are predictors of the genetic susceptibility to
diseases, calculated for individuals as weighted counts of thousands of risk variants in which …
diseases, calculated for individuals as weighted counts of thousands of risk variants in which …
The genetic basis of major depression
Major depressive disorder (MDD) is a common, debilitating, phenotypically heterogeneous
disorder with heritability ranges from 30% to 50%. Compared to other psychiatric disorders …
disorder with heritability ranges from 30% to 50%. Compared to other psychiatric disorders …
A survey of attitudes, anxiety status, and protective behaviors of the university students during the COVID-19 outbreak in Turkey
A new coronavirus disease began on 31 December 2019 in Wuhan/China and has caused
a global outbreak in only a few months resulting in millions being infected. In conjunction …
a global outbreak in only a few months resulting in millions being infected. In conjunction …
Burden of depression in China, 1990–2017: findings from the global burden of disease study 2017
X Ren, S Yu, W Dong, P Yin, X Xu, M Zhou - Journal of Affective Disorders, 2020 - Elsevier
Abstract Background Depression in China has risen from the 15th leading cause of all-
cause disability-adjusted life years (DALYs) in 1990 to the 10th in 2017. However, the …
cause disability-adjusted life years (DALYs) in 1990 to the 10th in 2017. However, the …
Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts
C Fabbri, SP Hagenaars, C John, AT Williams… - Molecular …, 2021 - nature.com
Abstract Treatment-resistant depression (TRD) is a major contributor to the disability caused
by major depressive disorder (MDD). Primary care electronic health records provide an …
by major depressive disorder (MDD). Primary care electronic health records provide an …
Psychometric properties and measurement invariance of the 7-item General Anxiety Disorder scale (GAD-7) in an Italian coronary heart disease population
T Bolgeo, R Di Matteo, N Simonelli, A Dal Molin… - Journal of Affective …, 2023 - Elsevier
Abstract Background Generalized Anxiety Disorder is predominant in coronary heart
disease (CHD) patients. 7-item Generalized Anxiety Disorder (GAD-7) scale psychometric …
disease (CHD) patients. 7-item Generalized Anxiety Disorder (GAD-7) scale psychometric …
Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid‐twenties
Abstract The Twins Early Development Study (TEDS) is a longitudinal study following a
cohort of twins born 1994–1996 in England and Wales. Of the 13,759 families who originally …
cohort of twins born 1994–1996 in England and Wales. Of the 13,759 families who originally …
[HTML][HTML] Comparison of symptom-based versus self-reported diagnostic measures of anxiety and depression disorders in the GLAD and COPING cohorts
Background Understanding and improving outcomes for people with anxiety or depression
often requires large sample sizes. To increase participation and reduce costs, such research …
often requires large sample sizes. To increase participation and reduce costs, such research …
Pre-pandemic mental health and disruptions to healthcare, economic and housing outcomes during the COVID-19 pandemic: evidence from 12 UK longitudinal …
Background The COVID-19 pandemic has disrupted lives and livelihoods, and people
already experiencing mental ill health may have been especially vulnerable. Aims Quantify …
already experiencing mental ill health may have been especially vulnerable. Aims Quantify …