Pathophysiology of spastic paresis. II: Emergence of muscle overactivity

JM Gracies - Muscle & Nerve: Official Journal of the American …, 2005 - Wiley Online Library
In the subacute and chronic stages of spastic paresis, stretch‐sensitive (spastic) muscle
overactivity emerges as a third fundamental mechanism of motor impairment, along with …

Spastic movement disorder: impaired reflex function and altered muscle mechanics

V Dietz, T Sinkjaer - The Lancet Neurology, 2007 - thelancet.com
In clinical practice, signs of exaggerated tendon tap reflexes associated with muscle
hypertonia are generally thought to be responsible for spastic movement disorders. Most …

Presynaptic inhibition in the vertebrate spinal cord revisited

P Rudomin, RF Schmidt - Experimental brain research, 1999 - Springer
The present review examines the experimental evidence supporting the existence of central
mechanisms able to modulate the synaptic effectiveness of sensory fibers ending in the …

Spasticity mechanisms–for the clinician

A Mukherjee, A Chakravarty - Frontiers in neurology, 2010 - frontiersin.org
Spasticity, a classical clinical manifestation of an upper motor neuron lesion, has been
traditionally and physiologically defined as a velocity dependent increase in muscle tone …

Transcutaneous spinal cord stimulation induces temporary attenuation of spasticity in individuals with spinal cord injury

US Hofstoetter, B Freundl, SM Danner… - Journal of …, 2020 - liebertpub.com
Epidural spinal cord stimulation (SCS) is currently regarded as a breakthrough procedure for
enabling movement after spinal cord injury (SCI), yet one of its original applications was for …

The spinal pathophysiology of spasticity–from a basic science point of view

JB Nielsen, C Crone, H Hultborn - Acta physiologica, 2007 - Wiley Online Library
Spasticity is a term, which was introduced to describe the velocity‐sensitive increased
resistance of a limb to manipulation in subjects with lesions of descending motor pathways …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Spasticity-assessment: a review

F Biering-Sørensen, JB Nielsen, K Klinge - Spinal cord, 2006 - nature.com
Study design: Review of the literature on the validity and reliability of assessment of
spasticity and spasms. Objectives: Evaluate the most frequently used methods for …

On the mechanism of the post-activation depression of the H-reflex in human subjects

H Hultborn, M Illert, J Nielsen, A Paul… - Experimental brain …, 1996 - Springer
It was demonstrated that the soleus H-reflex was depressed for more than 10 s following a
preceding passive dorsiflexion of the ankle joint. This depression was caused by activation …

Presynaptic inhibition and homosynaptic depression: a comparison between lower and upper limbs in normal human subjects and patients with hemiplegia

C Aymard, R Katz, C Lafitte, E Lo, A Pénicaud… - Brain, 2000 - academic.oup.com
Presynaptic inhibition of Ia terminals and postactivation depression at the Ia fibre–motor
neuron (MN) synapses were compared in the upper and lower limbs of both sides in …