With the continued increase of genomic information and computational analyses during the
recent years, the number of newly discovered calcium binding proteins (CaBPs) in …

Background Protein crystallins co me in three types (α, β and γ) and are found
predominantly in the eye, and particularly in the lens, where they are packed into a compact …

γ-Crystallins constitute the major protein component in the nucleus of the vertebrate eye
lens. Present at very high concentrations, they exhibit extreme solubility and thermodynamic …

Neisseria meningitidis causes bacterial meningitis and septicemia. It evades the host
complement system by upregulating expression of immune evasion factors in response to …

Mechanosensitive channels are ubiquitous and highly studied. However, the evolution of the
bacterial channels remains enigmatic. It can be argued that mechanosensitivity might be a …

The βγ-crystallin superfamily consists of evolutionarily related proteins with domain topology
similar to lens β-and γ-crystallins, formed from duplicated Greek key motifs. Ca2+ binding …

This review examines both recent and historical literature related to the biophysical
chemistry of the proteins in the ageing eye, with a particular focus on cataract development …

The βγ-crystallin superfamily contains both β-and γ-crystallins of the vertebrate eye lens and
the microbial calcium-binding proteins, all of which are characterized by a common double …

βγ-Crystallin-type double clamp (N/D)(N/D) XX (S/T) S motif is an established but sparsely
investigated motif for Ca 2+ binding. A βγ-crystallin domain is formed of two Greek key …

The crystallins (α, β and γ), major constituent proteins of eye lens fiber cells play their critical
role in maintaining the transparency and refractive index of the lens. Under different stress …