Iron deficiency anemia (IDA) is a major problem in chronic kidney disease (CKD), causing
increased mortality. Ferritin stores iron, representing iron status. Hepcidin binds to …

Resistance to erythropoiesis-stimulating agents (ESAs) has been observed in a
considerable proportion of patients with chronic kidney disease (CKD) and it is reportedly …

Abstract Recently, the Kidney Disease: Improving Global Outcomes (KDIGO) group has
produced comprehensive clinical practice guidelines for the management of anaemia in …

Background Anemia associated with chronic kidney disease (CKD) often requires treatment
with recombinant human erythropoietin (EPO). Hypoxia-inducible factor− prolyl hydroxylase …

Iron is an essential metal for cell survival that is regulated by the peptide hormone hepcidin.
However, its influence on certain diseases is directly related to iron metabolism or …

Anemia is common in patients with chronic kidney disease (CKD) and results from the
dysregulation of iron metabolism and erythropoiesis. Hepcidin is a key regulator of iron …

Dysregulated iron homeostasis plays a central role in the development of anemia of chronic
kidney disease (CKD) and is a major contributor toward resistance to treatment with …

The metabolism of hepcidin is profoundly modified in chronic kidney disease (CKD). We
investigated its relation to iron disorders, inflammation and hemoglobin (Hb) level in 199 …

Anemia is a complication of chronic kidney disease (CKD), primarily due to insufficient
secretion of erythropoietin (EPO) by the kidney. Erythropoiesis-stimulating agents (ESAs) …

Hepcidin-25, the bioactive form of hepcidin, is a key regulator of iron homeostasis as it
induces internalization and degradation of ferroportin, a cellular iron exporter on …