New insight on the potential detrimental effect of metabolic syndrome on the Alzheimer disease neuropathology: Mechanistic role

NH Ali, HM Al‐Kuraishy, AI Al‐Gareeb… - Journal of Cellular …, 2024 - Wiley Online Library
The metabolic syndrome or syndrome X is a clustering of different components counting
insulin resistance (IR), glucose intolerance, visceral obesity, hypertension and dyslipidemia …

Protective effects of a natural product, paeoniflorin, on ischemia reperfusion injury on rat ovary tissue: histopathological, immunohistochemical, and biochemical study

P Bayram, SA Karamese, HS Erol… - Journal of …, 2023 - Taylor & Francis
In this study, the main hypothesis is that paeoniflorin may inhibit some cellular processes
such as oxidative stress and inflammation. For this reason, we aimed to investigate the …

Integrated transcriptome and metabolome analysis to investigate the mechanism of intranasal insulin treatment in a rat model of vascular dementia

L Tang, Y Wang, X Gong, J Xiang, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Introduction: Insulin has an effect on neurodegenerative diseases. However, the role and
mechanism of insulin in vascular dementia (VD) and its underlying mechanism are …

Insulin signaling promotes neurogenesis in the brain of adult zebrafish

L Gence, D Fernezelian, O Meilhac… - Journal of …, 2023 - Wiley Online Library
Insulin is a peptide hormone that plays a central role in the regulation of circulating blood
glucose in vertebrates, including zebrafish. Increasing evidence has demonstrated the …

Influence of topical NPH-insulin use on wound healing and oxidative stress in alkali corneal burns: an experimental study in a rabbit model

B Kurt, L Balyen, O Atakişi, S Yiğit, U Aydin… - Iranian Journal of …, 2024 - ijvr.shirazu.ac.ir
Background: In acute alkali corneal burns, the routine treatment protocol includes
suppressing inflammation using corticosteroids. In recent years, there has been a growing …

A cafeteria diet blunts effects of exercise on adult hippocampal neurogenesis but not neurogenesis-dependent behaviours in adult male rats

MHC Nota, S Dohm-Hansen, S Nicolas, EP Harris… - bioRxiv, 2024 - biorxiv.org
Animal studies have shown that a cafeteria (CAF) diet (high in saturated fat and sugar), is
associated with memory impairments and increased anxiety, while exercise can enhance …