Artemether and praziquantel: origin, mode of action, impact, and suggested application for effective control of human schistosomiasis

R Bergquist, H Elmorshedy - Tropical medicine and infectious disease, 2018 - mdpi.com
The stumbling block for the continued, single-drug use of praziquantel (PZQ) against
schistosomiasis is less justified by the risk of drug resistance than by the fact that this drug is …

Human schistosomiasis in the Middle East and North Africa region

R Barakat, H El Morshedy, A Farghaly - Neglected Tropical Diseases …, 2014 - Springer
Human schistosomiasis is one of the most common Neglected Tropical Diseases (NTDs); it
is an intravascular parasite caused by the trematode blood fluke (Schistosoma). Most human …

[HTML][HTML] Efficacy and safety of arachidonic acid for treatment of school-age children in Schistosoma mansoni high-endemicity regions

R Barakat, NE Abou El-Ela, S Sharaf… - The American journal …, 2015 - ncbi.nlm.nih.gov
Arachidonic acid (ARA), an omega-6 fatty acid, is a potent schistosomicide that displayed
significant and safe therapeutic effects in Schistosoma mansoni-infected schoolchildren in S …

[HTML][HTML] Prophylactic effect of artemether on human schistosomiasis mansoni among Egyptian children: A randomized controlled trial

H Elmorshedy, M Tanner, RN Bergquist, S Sharaf… - Acta tropica, 2016 - Elsevier
A double-blind, randomized controlled trial was conducted in an endemic focus for
Schistosoma mansoni in Kafr El-Sheikh Governorate, Northern Nile Delta, Egypt, to evaluate …

Can human schistosomiasis mansoni control be sustained in high-risk transmission foci in Egypt?

H Elmorshedy, R Bergquist, NEA El-Ela, SM Eassa… - Parasites & vectors, 2015 - Springer
Background Control of human schistosomiasis remains a longstanding issue on the agenda
of the Egyptian Ministry of Health and Population (MOHP). Substantial impact on morbidity …

[HTML][HTML] Test, treat, track, test, and treat active surveillance toward elimination of schistosomiasis: a feasibility study

RMR Ramzy, A Rabiee, KM Abd Elaziz… - The American Journal …, 2020 - ncbi.nlm.nih.gov
We assessed the feasibility of using a test, treat, track, test, and treat (5T) active surveillance
strategy to identify and treat individuals with schistosomiasis in three very low-prevalence …

Schistosoma mansoni soluble egg antigens enhance HCV replication in mammalian cells

MM Bahgat, MAE El-Far, AA Mesalam… - The Journal of Infection …, 2010 - jidc.org
Background: This work demonstrates successful propagation of HCV in HepG2 and human
blood cells as well as viral shedding into their culture media. The influence of Schistosoma …

Schistosomiasis–a rich vein of research

P Hagan - Parasitology, 2009 - cambridge.org
The expansion in the volume of research activity over the last 100 years and the
acceleration of technological change that underpins the nature and, to a lesser extent, the …

Role of CCR5Δ32 mutation in protecting patients with Schistosoma mansoni infection against hepatitis C viral infection or progression

AA El-Moamly, MA El-Sweify, RM Rashad… - Parasitology …, 2013 - Springer
Schistosomiasis has been incriminated in the significant increase in hepatitis C virus (HCV)
infections, although the association has not been adequately explained. We hypothesized …

[PDF][PDF] Katayama fever with rare presentation

MS Mogawer, MEE Behiry, AMA Ghany - MOJ Clin Med Case Rep, 2019 - researchgate.net
Report on a 16-year-old male came to emergency unit of Internal medicine department at
Kasr Alaini hospital with chronic diarrhea of 5months' duration, significant weight loss, fever …