Embryonic stem cells neural differentiation qualifies the role of Wnt/β-Catenin signals in human telencephalic specification and regionalization
C Nicoleau, C Varela, C Bonnefond, Y Maury… - Stem …, 2013 - academic.oup.com
Wnt-ligands are among key morphogens that mediate patterning of the anterior territories of
the developing brain in mammals. We qualified the role of Wnt-signals in regional …
the developing brain in mammals. We qualified the role of Wnt-signals in regional …
Early transcriptional changes linked to naturally occurring Huntington's disease mutations in neural derivatives of human embryonic stem cells
M Feyeux, F Bourgois-Rocha, A Redfern… - Human molecular …, 2012 - academic.oup.com
Huntington's disease (HD) is characterized by a late clinical onset despite ubiquitous
expression of the mutant gene at all developmental stages. How mutant huntingtin impacts …
expression of the mutant gene at all developmental stages. How mutant huntingtin impacts …
Differentiation of human embryonic stem cells
J Xu - US Patent 9,096,832, 2015 - Google Patents
The present invention provides methods to promote the differentiation of pluripotent stem
cells. In particular, the present invention provides an improved method for the formation of …
cells. In particular, the present invention provides an improved method for the formation of …
High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of …
J Charbord, P Poydenot, C Bonnefond, M Feyeux… - Stem Cells, 2013 - academic.oup.com
Decreased expression of neuronal genes such as brain-derived neurotrophic factor (BDNF)
is associated with several neurological disorders. One molecular mechanism associated …
is associated with several neurological disorders. One molecular mechanism associated …
Differentiation of human embryonic stem cells
J Xu - US Patent 9,150,833, 2015 - Google Patents
3. 6 A 1992 SR et al cells. In particular, the present invention provides a method to s sys-
childer et al. 5,713,957 A 2f1998 Steele et al. produce cells expressing markers …
childer et al. 5,713,957 A 2f1998 Steele et al. produce cells expressing markers …
Differentiation of pluripotent stem cells
A Rezania - US Patent 9,181,528, 2015 - Google Patents
US9181528B2 - Differentiation of pluripotent stem cells - Google Patents US9181528B2 -
Differentiation of pluripotent stem cells - Google Patents Differentiation of pluripotent stem cells …
Differentiation of pluripotent stem cells - Google Patents Differentiation of pluripotent stem cells …
Differentiation of human embryonic stem cells into pancreatic endocrine cells using HB9 regulators
A Rezania - US Patent 10,138,465, 2018 - Google Patents
The present invention provides methods to promote differentiation of pluripotent stem cells to
pancreatic endoderm cells expressing PDX1, NKX6. 1, and HB9. In particular, the methods …
pancreatic endoderm cells expressing PDX1, NKX6. 1, and HB9. In particular, the methods …
Use of small molecules to enhance MAFA expression in pancreatic endocrine cells
A Rezania - US Patent 10,006,006, 2018 - Google Patents
The present invention provides methods, cell cultures and differentiation media to promote
differentiation of pluripotent stem cells to pancreatic endocrine cells of a mature phenotype …
differentiation of pluripotent stem cells to pancreatic endocrine cells of a mature phenotype …
Differentiation of human embryonic stem cells into pancreatic endocrine cells
A Rezania - US Patent 10,066,210, 2018 - Google Patents
US10066210B2 - Differentiation of human embryonic stem cells into pancreatic endocrine cells -
Google Patents US10066210B2 - Differentiation of human embryonic stem cells into pancreatic …
Google Patents US10066210B2 - Differentiation of human embryonic stem cells into pancreatic …
Differentiation of human embryonic stem cells
A Rezania - US Patent 9,528,090, 2016 - Google Patents
3,209,652 A 10/1965 Burgsmueller 3,845,641 A 11, 1974 Waller 3,935,067 A 1/1976 Thayer
4,499,802 A 2/1985 Simpson 4,537,773. A 8, 1985 Shenvi 4,557,264 A 12/1985 Hinsch …
4,499,802 A 2/1985 Simpson 4,537,773. A 8, 1985 Shenvi 4,557,264 A 12/1985 Hinsch …