The sixth edition of the WHO manual for human semen analysis: a critical review and SWOT analysis

F Boitrelle, R Shah, R Saleh, R Henkel, H Kandil… - Life, 2021 - mdpi.com
Semen analysis is the cornerstone of male fertility evaluation with WHO guidelines providing
the basis for procedural standardization and reference values worldwide. The first WHO …

[HTML][HTML] Male infertility and oxidative stress: a focus on the underlying mechanisms

RJ Aitken, JR Drevet, A Moazamian, P Gharagozloo - Antioxidants, 2022 - mdpi.com
Reactive oxygen species (ROS) play a critical role in defining the functional competence of
human spermatozoa. When generated in moderate amounts, ROS promote sperm …

The impact of oxidative stress in male infertility

A Mannucci, FR Argento, E Fini, ME Coccia… - Frontiers in Molecular …, 2022 - frontiersin.org
At present infertility is affecting about 15% of couples and male factor is responsible for
almost 50% of infertility cases. Oxidative stress, due to enhanced Reactive Oxygen Species …

Oxidative stress and male infertility

S Bisht, M Faiq, M Tolahunase, R Dada - Nature Reviews Urology, 2017 - nature.com
DNA damage, largely owing to oxidative stress, is a leading cause of defective sperm
function. High levels of oxidative stress result in damage to sperm DNA, RNA transcripts …

Reactive oxygen species as mediators of sperm capacitation and pathological damage

RJ Aitken - Molecular reproduction and development, 2017 - Wiley Online Library
Oxidative stress plays a major role in the life and death of mammalian spermatozoa. These
gametes are professional generators of reactive oxygen species (ROS), which appear to …

[HTML][HTML] Impact of oxidative stress on male and female germ cells: implications for fertility

RJ Aitken - Reproduction, 2020 - rep.bioscientifica.com
Male and female germ lines are vulnerable to oxidative stress. In spermatozoa, such stress
triggers a lipid peroxidation cascade that culminates in the generation of electrophilic lipid …

Glutathione peroxidases

R Brigelius-Flohé, M Maiorino - … et Biophysica Acta (BBA)-General Subjects, 2013 - Elsevier
BACKGROUND: With increasing evidence that hydroperoxides are not only toxic but rather
exert essential physiological functions, also hydroperoxide removing enzymes have to be re …

[HTML][HTML] Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios

A Agarwal, A Majzoub, SC Esteves, E Ko… - Translational …, 2016 - ncbi.nlm.nih.gov
Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for
male fertility evaluation. While its detrimental implications on sperm function were …

Advances in cryopreservation of bull sperm

MR Ugur, A Saber Abdelrahman, HC Evans… - Frontiers in veterinary …, 2019 - frontiersin.org
Cryopreservation of semen and artificial insemination have an important, positive impact on
cattle production, and product quality. Through the use of cryopreserved semen and artificial …

Molecular changes induced by oxidative stress that impair human sperm motility

K Nowicka-Bauer, B Nixon - Antioxidants, 2020 - mdpi.com
A state of oxidative stress (OS) and the presence of reactive oxygen species (ROS) in the
male reproductive tract are strongly correlated with infertility. While physiological levels of …