[HTML][HTML] Molecular, cellular and systemic aspects of epithelial ovarian cancer and its tumor microenvironment

E Schoutrop, L Moyano-Galceran, S Lheureux… - Seminars in cancer …, 2022 - Elsevier
Ovarian cancer encompasses a heterogeneous group of malignancies that involve the
ovaries, fallopian tubes and the peritoneal cavity. Despite major advances made within the …

Heterogeneity and treatment landscape of ovarian carcinoma

AC Veneziani, E Gonzalez-Ochoa, H Alqaisi… - Nature Reviews …, 2023 - nature.com
Ovarian carcinoma is characterized by heterogeneity at the molecular, cellular and
anatomical levels, both spatially and temporally. This heterogeneity affects response to …

The high-grade serous ovarian cancer metastasis and chemoresistance in 3D models

V Tadić, W Zhang, A Brozovic - … et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
High-grade serous ovarian cancer (HGSOC) is the most frequent and aggressive type of
epithelial ovarian cancer, with high recurrence rate and chemoresistance being the main …

[HTML][HTML] (Dis) similarities between the decidual and tumor microenvironment

J Krstic, A Deutsch, J Fuchs, M Gauster… - Biomedicines, 2022 - mdpi.com
Placenta-specific trophoblast and tumor cells exhibit many common characteristics.
Trophoblast cells invade maternal tissues while being tolerated by the maternal immune …

Three-Dimensional Culture for In Vitro Folliculogenesis in the Aspect of Methods and Materials

S Khunmanee, H Park - Tissue Engineering Part B: Reviews, 2022 - liebertpub.com
In vitro ovarian follicle culture is a reproduction technique used to obtain fertilizable oocytes,
for overcoming fertility issues due to premature ovarian failure. This requires the …

Injectable three-dimensional tumor microenvironments to study mechanobiology in ovarian cancer

EN Horst, CM Novak, K Burkhard, CS Snyder, R Verma… - Acta biomaterialia, 2022 - Elsevier
Epithelial ovarian cancers are among the most aggressive forms of gynecological
malignancies. Despite the advent of poly adenosine diphosphate-ribose polymerase …

[HTML][HTML] Novel frontiers in urogenital cancers: from molecular bases to preclinical models to tailor personalized treatments in ovarian and prostate cancer patients

G De Lazzari, A Opattova, S Arena - Journal of Experimental & Clinical …, 2024 - Springer
Over the last few decades, the incidence of urogenital cancers has exhibited diverse trends
influenced by screening programs and geographical variations. Among women, there has …

[HTML][HTML] Patient-derived in vitro models of ovarian cancer: powerful tools to explore the biology of the disease and develop personalized treatments

C Battistini, U Cavallaro - Cancers, 2023 - mdpi.com
Simple Summary Ovarian cancer (OC) is a highly lethal neoplasm with a poor rate of
response to current treatment. A prerequisite to designing and validating innovative and …

Paracrine Ovarian Cancer Cell‐Derived CSF1 Signaling Regulates Macrophage Migration Dynamics in a 3D Microfluidic Model that Recapitulates in vivo Infiltration …

AL Scott, DE Jazwinska, DG Kulawiec… - Advanced …, 2024 - Wiley Online Library
A high density of macrophages in the ovarian cancer microenvironment is associated with
disease progression and poor outcomes. Understanding cancer‐macrophage interaction …

[HTML][HTML] Comprehensive single-cell and bulk RNA-seq analyses reveal a novel CD8+ T cell-associated prognostic signature in ovarian cancer

YL Han, Z Fang, ZJ Gao, WG Li, J Yang - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
CD8+ T cells play pivotal roles in combating intracellular pathogens and eliminating
malignant cells in cancer. However, the prognostic role of CD8+ T cells in ovarian carcinoma …