Atherosclerosis is a chronic disease of the arterial wall where both innate and adaptive
immunoinflammatory mechanisms are involved. Inflammation is central at all stages of …

Vascular inflammation is associated with and in large part driven by changes in the
leukocyte compartment of the vessel wall. Here, we focus on monocyte influx during …

Lipoxygenases (LOX) form a family of lipid peroxidizing enzymes, which have been
implicated in a number of physiological processes and in the pathogenesis of inflammatory …

Monocytes/macrophages are innate immune cells that play a crucial role in the resolution of
inflammation. In the presence of the Th2 cytokines interleukin-4 (IL-4) and interleukin-13 (IL …

12/15-Lipoxygenases (12/15-LOX) are members of the LOX family, which are expressed in
mammals by monocytes and macrophages following induction by the T helper type 2 …

Relevance of mitogen-activated protein kinases ERK, JNK, and p38 in the regulation of
myeloid differentiation. The MAPKs are a family of serine/threonine kinases that play an …

Asthma is a chronic allergic inflammatory disease, the initiation and progression of which is
dependent on the cytokines interleukin (IL)-4 and IL-13 acting through related receptor …

Combined allergic rhinitis and asthma syndrome (CARAS) causes chronic respiratory
inflammation in allergic individuals. Long-term exposure to particulate matter 2.5 (PM2. 5; …

Signal identified by which basophils express cytokines involved in allergy independent of
the more classically studied basophil activation pathway induced by cross-linking of surface …

IL-6 has been shown to play a major role in collagen up-regulation process during cardiac
hypertrophy, although the precise mechanism is still not known. In this study we have …