Simple Summary In the United States, over 13,000 patients are diagnosed with soft tissue
sarcoma annually leading to over 5000 deaths per year despite aggressive treatments …

Introduction Retroperitoneal sarcoma (RPS) is a rare disease accounting for 0.1%–0.2% of
all malignancies. Management of RPS is complex and requires multidisciplinary, tailored …

Osteosarcoma is a rare bone tumor that occurs in young adults with a subsequent peak in
the fifth decade. Neoadjuvant and adjuvant chemotherapy and surgery cure approximately …

Purpose The lung is the most frequent site of metastasis in patients with sarcoma.
Pulmonary metastasectomy is the most common treatment performed. Stereotactic body …

Importance Active therapeutic combinations, such as trabectedin and radiotherapy, offer
potentially higher dimensional response in second-line treatment of advanced soft-tissue …

Sarcoma comprises a heterogeneous group of histologic subtypes with a propensity to
metastasize to the lungs. Isolated pulmonary metastases occur in as many as 20% of …

Simple Summary Radiation therapy (RT) is an integral part of the treatment of adult soft-
tissue sarcomas (STS). Although mainly used as perioperative therapy to increase local …

Purpose Given the relative radioresistance of sarcomas and their often large size,
conventional palliative radiation therapy (RT) often offers limited tumor control and symptom …

Local management of adult soft tissue sarcoma of the extremities has evolved over the past
decades. Until the 1970s, radical surgery (amputations) was the standard therapeutic …

Abstract Purpose of Review The management of metastatic disease is evolving. As systemic
therapies continue to improve, there is increasing recognition that local therapy to distant …