[HTML][HTML] Turning cold tumors into hot tumors by improving T-cell infiltration

YT Liu, ZJ Sun - Theranostics, 2021 - ncbi.nlm.nih.gov
Immunotherapy, represented by immune checkpoint inhibitors (ICIs), has greatly improved
the clinical efficacy of malignant tumor therapy. ICI-mediated antitumor responses depend …

Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Biomimetic nanoerythrosome‐coated aptamer–DNA tetrahedron/maytansine conjugates: pH‐responsive and targeted cytotoxicity for HER2‐positive breast cancer

W Ma, Y Yang, J Zhu, W Jia, T Zhang, Z Liu… - Advanced …, 2022 - Wiley Online Library
DNA materials have emerged as potential nanocarriers for targeted cancer therapy to
precisely deliver cargos with specific purposes. The short half‐life and low bioavailability of …

Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy

C Zhang, Z Zeng, D Cui, S He, Y Jiang, J Li… - Nature …, 2021 - nature.com
Immunometabolic intervention has been applied to treat cancer via inhibition of certain
enzymes associated with intratumoral metabolism. However, small-molecule inhibitors and …

Engineered drug-loaded cellular membrane nanovesicles for efficient treatment of postsurgical cancer recurrence and metastasis

Y Yu, Q Cheng, X Ji, H Chen, W Zeng, X Zeng… - Science …, 2022 - science.org
Cancer recurrence and metastasis are still common causes of postsurgery death in patients
with solid tumors, suggesting that additional consolidation therapeutic strategies are …

Recent applications of immunomodulatory biomaterials for disease immunotherapy

H Dai, Q Fan, C Wang - Exploration, 2022 - Wiley Online Library
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

Cancer-erythrocyte hybrid membrane-camouflaged magnetic nanoparticles with enhanced photothermal-immunotherapy for ovarian cancer

J Xiong, M Wu, J Chen, Y Liu, Y Chen, G Fan, Y Liu… - ACS …, 2021 - ACS Publications
Cell-membrane-coated nanoparticles are widely studied due to their inherent cellular
properties, such as immune escape and homologous homing. A cell membrane coating can …

Boosting checkpoint immunotherapy with biomaterials

L Liu, Y Pan, C Zhao, P Huang, X Chen, L Rao - ACS nano, 2023 - ACS Publications
The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …

Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines

L Chen, H Qin, R Zhao, X Zhao, L Lin, Y Chen… - Science translational …, 2021 - science.org
Cancer vaccines based on resected tumors from patients have gained great interest as an
individualized cancer treatment strategy. However, eliciting a robust therapeutic effect with …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …