Despite significant advances in the field of cancer immunotherapy, the majority of patients
still do not benefit from treatment and must rely on traditional therapies. Dendritic cells have …

The skin is the outermost organ of the body and is continuously exposed to external
pathogens. Upon inflammation, various immune cells pass through, reside in or are …

Dendritic cells (DCs) are central regulators of the adaptive immune response, and as such
are necessary for T-cell-mediated cancer immunity. In particular, antitumoral responses …

Background Every day the skin is constantly exposed to several harmful factors that induce
oxidative stress. When the cells are incapable to maintain the balance between antioxidant …

Avermectins are a group of drugs that occurs naturally as a product of fermenting
Streptomyces avermitilis, an actinomycetes, isolated from the soil. Eight different structures …

T cells have crucial roles in protection against infection and cancer. Although the trafficking
of memory T cells around the body is integral to their capacity to provide immune protection …

Numerous scientific studies in recent years have shown significant skin and gut dysbiosis
among patients with psoriasis. A significant decrease in microbiome alpha-diversity …

Tissue-resident memory T (Trm) cells constitute a recently identified lymphocyte lineage that
occupies tissues without recirculating. They provide a first response against infections …

Intratumoral CD103+ dendritic cells (DCs) are necessary for anti-tumor immunity. Here we
evaluated the expression of immune regulators by CD103+ DCs in a murine model of breast …

CCR7 chemokine receptor stimulation induces rapid but transient dendritic cell (DC)
migration toward draining lymph nodes, which is critical for the initiation of protective …