Prostatic diseases are very common in male dogs, accounting for 3–10% of cases submitted
to the veterinary practitioners. Commonly reported canine prostatic disorders include …

Simple Summary Prostate cancer (PC) is one of the main types of cancer that affects the
male population worldwide. In recent decades, there has been a significant evolution in the …

Cancer stem cell (CSC) self-renewing and drug resistance cause treatment failure and
tumor recurrence. Osteosarcoma is an aggressive bone tumor characterized by biological …

Abstract The PTEN, AR, MDM2 and p53 protein network plays a central role in the
development of many human cancers, thus eliciting the development of targeted cancer …

An unusual variant of prostate adenocarcinoma (PC) expressing nuclear p63 in secretory
cells instead of the typical basal expression has been reported in men. Nevertheless, the …

Canine prostate adenocarcinoma (PAC) and transitional cell carcinoma (TCC) of prostate
and urinary bladder are highly invasive and metastatic tumors of closely neighbored organs …

Canine carcinomas have been considered natural models for human diseases; however,
the genomic profile of canine prostate cancers (PCs) has not been explored. In this study, 14 …

Background Vascular endothelial growth factor‐A (VEGF‐A) and its receptor, VEGF receptor‐
2 (VEGFR‐2), represent a complex family of angiogenic molecules consisting of different …

A limited number of species, including men and dogs, spontaneously develop prostate
cancer (PC). The histological and molecular relevance of canine PC as a model for the …

Simple Summary Prostatic diseases are important worldwide, being the prostate cancer
(PC) the most common tumor in men. Among the factors associated with PC development …