Polyoxazoline: A review article from polymerization to smart behaviors and biomedical applications

SN Mahand, S Aliakbarzadeh, A Moghaddam… - European Polymer …, 2022 - Elsevier
Abstract Poly (2-oxazoline) s are emerging innovative biomaterials that show analogous and
even preferable properties compared to well-known counterparts, especially poly (ethylene …

The chemistry of poly (2-oxazoline) s

B Verbraeken, BD Monnery, K Lava… - European Polymer …, 2017 - Elsevier
As we celebrate the 50th birthday of the discovery of poly (2-alkyl/aryl-2-oxazoline) s (PAOx)
this year we see a research field that is rapidly expanding after some lesser academic …

Poly (2‐oxazoline) s: A comprehensive overview of polymer structures and their physical properties

M Glassner, M Vergaelen… - Polymer …, 2018 - Wiley Online Library
Abstract Poly (2‐oxazoline) s (PAOx) are of increasing importance for a wide range of
applications, mostly in the biomedical field. This review describes the synthesis of 2 …

Poly (2‐oxazoline)‐and Poly (2‐oxazine)‐Based Self‐Assemblies, Polyplexes, and Drug Nanoformulations—An Update

A Zahoranová, R Luxenhofer - Advanced Healthcare Materials, 2021 - Wiley Online Library
Abstract For many decades, poly (2‐oxazoline) s and poly (2‐oxazine) s, two closely related
families of polymers, have led the life of a rather obscure research topic with only a few …

Poly (2-ethyl-2-oxazoline) conjugates with doxorubicin for cancer therapy: In vitro and in vivo evaluation and direct comparison to poly [N-(2-hydroxypropyl) …

O Sedlacek, BD Monnery, J Mattova, J Kucka, J Panek… - Biomaterials, 2017 - Elsevier
We designed and synthesized a new delivery system for the anticancer drug doxorubicin
based on a biocompatible hydrophilic poly (2-ethyl-2-oxazoline)(PEtOx) carrier with linear …

Double-network hydrogels including enzymatically crosslinked poly-(2-alkyl-2-oxazoline) s for 3D bioprinting of cartilage-engineering constructs

L Trachsel, C Johnbosco, T Lang, EM Benetti… - …, 2019 - ACS Publications
Double-network (DN) hydrogels are fabricated from poly (2-ethyl-2-oxazoline)(PEOXA)–
peptide conjugates, which can be enzymatically crosslinked in the presence of Sortase A …

Topology effects on the structural and physicochemical properties of polymer brushes

M Divandari, G Morgese, L Trachsel, M Romio… - …, 2017 - ACS Publications
The application of polymer “brushes”, with their unique physicochemical properties, has led
to a radical change in the way we functionalize biomaterials or formulate hybrids; however …

Poly (2‐oxazoline) Hydrogels: State‐of‐the‐Art and Emerging Applications

TR Dargaville, JR Park… - Macromolecular …, 2018 - Wiley Online Library
The synthesis of poly (2‐oxazoline) s has been known since the 1960s. In the last two
decades, they have risen in popularity thanks to improvements in their synthesis and the …

Next generation hemostatic materials based on NHS-ester functionalized poly (2-oxazoline) s

MA Boerman, E Roozen… - …, 2017 - ACS Publications
In order to prevent hemorrhage during surgical procedures, a wide range of hemostatic
agents have been developed. However, their efficacy is variable; hemostatic devices that …

Visualization and design of the functional group distribution during statistical copolymerization

PHM Van Steenberge, O Sedlacek… - Nature …, 2019 - nature.com
Even though functional copolymers with a low percentage of functional comonomer units (up
to 20 mol%) are widely used, for instance for the development of polymer therapeutics and …