Reactive intermediates as recognized chemical entities date back for over a century, and
among the earliest examples were simple free radicals, as identified in 1879, when it was …

Figure 73: The proposed catalyst/substrate interaction shown in Figure 73 corresponds to
the related sulfoxidation catalyzed by chiral phosphoric acid PA 5 (ref 133). Please note that …

Catalytic enantioselective boron–hydride additions to 1, 3-enynes, which afford allenyl–B
(pin)(pin= pinacolato) products, are disclosed. Transformations are promoted by a readily …

The first Cu-catalyzed asymmetric borylative cyclization of cyclohexadienone-containing 1, 6-
enynes is achieved through a tandem process: selective β-borylation of propargylic ether …

Chiral phosphoric acids (CPAs) have been used as efficient organocatalysts since the first
examples were reported 18 years ago by Akiyama and Terada. Although they were …

The development of α, α-disubstituted crotylboronate reagents is reported. Chiral Brønsted
acid-catalyzed asymmetric aldehyde addition with the developed E-crotylboron reagent …

We have developed a new three-component catalytic coupling reaction of alkynyl boronates,
diazomethanes, and aliphatic/aromatic ketones in the presence of BINOL derivatives. The …

The p K a values of 41 chiral phosphoric acid-family catalysts in DMSO were predicted using
the SMD/M06-2x/6-311++ G (2df, 2p)//B3LYP/6-31+ G (d) method for the first time. The study …

The widely applicable TRIP phosphoric acid catalyst has been immobilized on polystyrene
using a copolymerization-based strategy. The resin (PS-TRIP) has proven to be highly active …

A method to achieve enantioselective 1, 4-hydroboration of terminal and internal enynes to
access allenyl boronates under CuH catalysis is described. The reaction typically proceeds …