Statins and multiple noncardiovascular outcomes: umbrella review of meta-analyses of observational studies and randomized controlled trials
Background: Many effects of statins on non–cardiovascular disease (non-CVD) outcomes
have been reported. Purpose: To evaluate the quantity, validity, and credibility of evidence …
have been reported. Purpose: To evaluate the quantity, validity, and credibility of evidence …
p-Curve and p-Hacking in Observational Research
SB Bruns, JPA Ioannidis - PloS one, 2016 - journals.plos.org
The p-curve, the distribution of statistically significant p-values of published studies, has
been used to make inferences on the proportion of true effects and on the presence of p …
been used to make inferences on the proportion of true effects and on the presence of p …
Distributions of p-values smaller than. 05 in psychology: what is going on?
CHJ Hartgerink, RCM Van Aert, MB Nuijten… - PeerJ, 2016 - peerj.com
Previous studies provided mixed findings on pecularities in p-value distributions in
psychology. This paper examined 258,050 test results across 30,710 articles from eight high …
psychology. This paper examined 258,050 test results across 30,710 articles from eight high …
[HTML][HTML] How to trust a scientist
J De Ridder - Studies in History and Philosophy of Science, 2022 - Elsevier
Epistemic trust among scientists is inevitable. There are two questions about this:(1) What is
the content of this trust, what do scientists trust each other for?(2) Is such trust epistemically …
the content of this trust, what do scientists trust each other for?(2) Is such trust epistemically …
[HTML][HTML] A surge of p-values between 0.041 and 0.049 in recent decades (but negative results are increasing rapidly too)
JCF De Winter, D Dodou - PeerJ, 2015 - peerj.com
It is known that statistically significant (positive) results are more likely to be published than
non-significant (negative) results. However, it has been unclear whether any increasing …
non-significant (negative) results. However, it has been unclear whether any increasing …
The distribution of P-values in medical research articles suggested selective reporting associated with statistical significance
TV Perneger, C Combescure - Journal of clinical epidemiology, 2017 - Elsevier
Objectives Published P-values provide a window into the global enterprise of medical
research. The aim of this study was to use the distribution of published P-values to estimate …
research. The aim of this study was to use the distribution of published P-values to estimate …
Systematic assessment of pharmaceutical prescriptions in association with cancer risk: a method to conduct a population-wide medication-wide longitudinal study
It is a public health priority to identify the adverse and non-adverse associations between
pharmaceutical medications and cancer. We search for and evaluate associations between …
pharmaceutical medications and cancer. We search for and evaluate associations between …
Estimating the false discovery risk of (randomized) clinical trials in medical journals based on published p-values
U Schimmack, F Bartoš - Plos one, 2023 - journals.plos.org
The influential claim that most published results are false raised concerns about the
trustworthiness and integrity of science. Since then, there have been numerous attempts to …
trustworthiness and integrity of science. Since then, there have been numerous attempts to …
Limitations of empirical calibration of p‐values using observational data
S Gruber, E Tchetgen Tchetgen - Statistics in medicine, 2016 - Wiley Online Library
Controversy over non‐reproducible published research reporting a statistically significant
result has produced substantial discussion in the literature. p‐value calibration is a recently …
result has produced substantial discussion in the literature. p‐value calibration is a recently …