Deamination of DNA bases can occur spontaneously, generating highly mutagenic lesions
such as uracil, hypoxanthine, and xanthine. When cells are under oxidative stress that is …

All crystal structures of A‐DNA duplexes exhibit a typical crystal packing, with the termini of
one molecule abutting the shallow grooves of symmetry related neighbors, while all other …

When DNA is bent around a protein, it must distort. The distortion occurs by changes in the
conformation of successive dinucleotide steps. Bending does not necessarily occur …

This paper is concerned with an investigation of the geometry and structure of DNA as
revealed by X–ray diffraction of single crystal oligomeric structures. A database of atomic …

We have purified a novel endonuclease from Escherichia coli that recognizes deoxyinosine,
a deamination product of deoxyadenosine in DNA. This activity, which we named …

Inosine is one of the most common post-transcriptional modifications. Since its discovery, it
has been noted for its ability to contribute to non-Watson-Crick interactions within RNA …

The replicative and translational machinery utilizes the unique geometry of canonical G· C
and A· T/U Watson–Crick base pairs to discriminate against DNA and RNA mismatches in …

Extensive analyses of the base-pairing properties of deoxyinosine to A, C, G and T were
carried out by measuring the hybridisation of oligonucleotides with deoxyinosine In various …

Nucleic acids constitute the library of genetic information for all living organisms. They also
play a regulatory role in many biological events concerned with the utilization of genetic …

Sequence-dependent bending of the helical axes in 112 oligonucleotide duplex crystal
structures resident in the Nucleic Acid Database have been analyzed and compared with …