A mechanistic view of polybrominated diphenyl ether (PBDE) developmental neurotoxicity

LG Costa, R de Laat, S Tagliaferri, C Pellacani - Toxicology letters, 2014 - Elsevier
Polybrominated diphenyl ethers (PBDEs), extensively used in the past few decades as flame
retardants in a variety of consumer products, have become world-wide persistent …

Neurotoxicity of brominated flame retardants:(in) direct effects of parent and hydroxylated polybrominated diphenyl ethers on the (developing) nervous system

MML Dingemans, M van den Berg… - Environmental health …, 2011 - ehp.niehs.nih.gov
Background/objective: Polybrominated diphenyl ethers (PBDEs) and their hydroxylated (OH-
) or methoxylated forms have been detected in humans. Because this raises concern about …

Overview and recent advances in electrochemical sensing of glutathione–A review

M Hanko, Ľ Švorc, A Planková, P Mikuš - Analytica chimica acta, 2019 - Elsevier
The present paper is aimed at providing an overview of the recent advances in the
electrochemical sensing of glutathione (GSH), an important electrochemically and …

Polybrominated Diphenyl Ethers Induce Developmental Neurotoxicity in a Human in Vitro Model: Evidence for Endocrine Disruption

T Schreiber, K Gassmann, C Götz… - Environmental …, 2010 - ehp.niehs.nih.gov
Background Polybrominated diphenyl ethers (PBDEs) are persistent and bioaccumulative
flame retardants, which are found in rising concentrations in human tissues. They are of …

[HTML][HTML] Effects of 2, 2′, 4, 4′-tetrabromodiphenyl ether (BDE-47) on reproductive and endocrine function in female zebrafish (Danio rerio)

X Shi, R Wu, X Wang, W Huang, S Zheng… - Ecotoxicology and …, 2022 - Elsevier
Abstract Background Polybrominated diphenyl ethers (PBDEs), a group of brominated flame
retardants (BFRs), were reported exist extensively in various ecological environmental …

Cytotoxic and genotoxic effects of the flame retardants (PBDE-47, PBDE-99 and PBDE-209) in human bronchial epithelial cells

AM Montalbano, GD Albano, G Anzalone, M Moscato… - Chemosphere, 2020 - Elsevier
Polybrominated diphenyl ethers (PBDEs) are widespread as flame-retardants in different
types of consumer products. PBDEs present in the air or dust and their inhalation can …

Mechanisms involved in the neurotoxic effects of environmental toxicants such as polychlorinated biphenyls and brominated flame retardants

F Fonnum, E Mariussen - Journal of neurochemistry, 2009 - Wiley Online Library
Many toxic substances have been distributed to the environment, some of which have
properties that promote accumulation and biomagnification in living organisms …

Multifactorial origin of neurodevelopmental disorders: approaches to understanding complex etiologies

A De Felice, L Ricceri, A Venerosi, F Chiarotti… - Toxics, 2015 - mdpi.com
A significant body of evidence supports the multifactorial etiology of neurodevelopmental
disorders (NDDs) affecting children. The present review focuses on early exposure to …

Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes

M Schmidt, R Dringen - Frontiers in neuroenergetics, 2009 - frontiersin.org
Iodoacetamide (IAA) and iodoacetate (IA) have frequently been used to inhibit glycolysis,
since these compounds are known for their ability to irreversibly inhibit the glycolytic enzyme …

Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells

M Farina, F Campos, I Vendrell… - Toxicological …, 2009 - academic.oup.com
Methylmercury (MeHg) is an environmental neurotoxicant whose molecular mechanisms
underlying toxicity remain elusive. Here, we investigated molecular events involved in MeHg …