The great clinical success of cisplatin and its derivatives has convinced people that metal
complexes could play a more significant role in human cancer therapy. However, targeting …

Metals play vital roles in nutrients and medicines and provide chemical functionalities that
are not accessible to purely organic compounds. At least 10 metals are essential for human …

Platinum (Pt)-based anticancer drugs such as cisplatin have been used to treat various
cancers. However, they have some limitations including poor selectivity and toxicity towards …

Cancer is rapidly becoming the top killer in the world. Most of the FDA approved anticancer
drugs are organic molecules, while metallodrugs are very scarce. The advent of the first …

In recent years, the number of people suffering from cancer and multidrug-resistant
infections has sharply increased, leaving humanity without any choice but to search for new …

The endoplasmic reticulum (ER) has recently emerged as a promising target for anticancer
agents. Cytotoxic compounds that target the ER often exhibit selectivity for cancer cells over …

The redox properties of both metals and ligands in transition metal complexes offer unusual
routes for new mechanisms of anticancer therapy. Metal complexes can introduce artificial …

This review concentrates on recent developments in ruthenium Schiff bases, whose steric
and electronic characteristics can be manipulated easily by selecting suitable condensing …

Antimicrobial resistance, caused by persistent adaptation and growing resistance of
pathogenic bacteria to overprescribed antibiotics, poses one of the most serious and urgent …

A series of novel C, N-cyclometalated benzimidazole ruthenium (II) and iridium (III)
complexes of the types [(η6-p-cymene) RuCl (κ2-N, CL)] and [(η5-C5Me5) IrCl (κ2-N …