Hydra's almost unlimited regenerative potential is based on Wnt signaling, but so far it is
unknown how the injury stimulus is transmitted to discrete patterning fates in head and foot …

A fundamental step in regeneration is rapid growth to replace lost tissue. Cells must
generate sufficient lipids, nucleotides, and proteins to fuel rapid cell division. To define …

AICP is a crucial process that maintaining tissue homeostasis and regeneration. In the past,
cell death was perceived merely as a means to discard cells without functional …

The pharyngula stage of vertebrate development is characterized by stereotypical
arrangement of ectoderm, mesoderm, and neural tissues from the anterior spinal cord to the …

Regenerative potential is widespread but unevenly distributed across animals. However, our
understanding of the molecular mechanisms underlying regenerative processes is limited to …

The transforming growth factor-β (TGF-β) gene family is unique to animals and is involved in
various important processes including tissue regeneration. Here, we identified 52 TGF-β …

The wood frog, Rana sylvatica (aka Lithobates sylvaticus) is the main model for studies of
natural freeze tolerance among amphibians living in seasonally cold climates. During …

Many species of sea cucumbers (Echinodermata, Holothuroidea) perform evisceration, ie,
ejection of internal organs including digestive tracts when responding to environmental …

Urodelean amphibians can regenerate the tail and the spinal cord (SC) and maintain this
ability throughout their life. This clearly distinguishes these animals from mammals. The …

Wnt signal is crucial to correctly regenerate tissues along the original axis in many animals.
Lizards are able to regenerate their tails spontaneously, while the anterior-posterior axis …