A scoping review and meta-analysis of anti-CGRP monoclonal antibodies: predicting response

JB Hong, KS Lange, LH Overeem, P Triller, B Raffaelli… - Pharmaceuticals, 2023 - mdpi.com
Calcitonin gene-related peptide-targeted monoclonal antibodies (CGRP mAbs) are
increasingly being used as preventive treatments for migraine. Their effectiveness and …

Monoclonal antibodies against calcitonin gene-related peptide for migraine prophylaxis: a systematic review of real-world data

AR Pavelic, C Wöber, F Riederer, K Zebenholzer - Cells, 2022 - mdpi.com
Objective: To perform a systematic review of real-world outcomes for anti-CGRP-mAbs.
Methods: Following the PRISMA guidelines, we searched PubMed for real-world data of …

Clinical evaluation of super-responders vs. non-responders to CGRP (-receptor) monoclonal antibodies: a real-world experience

B Raffaelli, M Fitzek, LH Overeem, E Storch… - The Journal of …, 2023 - Springer
Background Clinical trials and real-world studies revealed a spectrum of response to CGRP
(-receptor) monoclonal antibodies (mAbs) in migraine prophylaxis, ranging from no effect at …

Predicting response to CGRP-monoclonal antibodies in patients with migraine in Japan: a single-centre retrospective observational study

K Ihara, S Ohtani, N Watanabe, N Takahashi… - The Journal of …, 2023 - Springer
Background Anti-calcitonin gene-related peptide monoclonal antibodies (CGRPmAbs) are a
favourable option for patients with migraine who experience distressful headache disability …

The Registry for Migraine (REFORM) study: methodology, demographics, and baseline clinical characteristics

WK Karlsson, H Ashina, CK Cullum… - The Journal of …, 2023 - Springer
Background Erenumab has demonstrated effectiveness for prevention of migraine attacks,
but the treatment is costly, and a considerable proportion of patients do not respond to it. The …

Methodological considerations on real-world evidence studies of monoclonal antibodies against the CGRP-pathway for migraine: a systematic review

N Vandenbussche, K Pisarek, K Paemeleire - The Journal of Headache …, 2023 - Springer
Background Real-world data are accumulating on the effectiveness, tolerability and safety of
anti-calcitonin gene-related peptide pathway monoclonal antibodies for the preventive …

Epigenetic connection of the calcitonin gene-related peptide and its potential in migraine

M Fila, A Sobczuk, E Pawlowska, J Blasiak - International journal of …, 2022 - mdpi.com
The calcitonin gene-related peptide (CGRP) is implicated in the pathogenesis of several
pain-related syndromes, including migraine. Targeting CGRP and its receptor by their …

An observational study on monoclonal antibodies against calcitonin‐gene‐related peptide and its receptor

F Schiano di Cola, M Bolchini… - European Journal of …, 2023 - Wiley Online Library
Background and purpose Based on their pharmacological target, two classes of calcitonin‐
gene‐related peptide (CGRP) monoclonal antibodies (mAbs) have been identified …

Conversion from chronic to episodic migraine in patients treated with galcanezumab in real life in Italy: the 12-month observational, longitudinal, cohort multicenter …

C Altamura, N Brunelli, M Marcosano, C Aurilia… - Journal of …, 2022 - Springer
Objective To investigate in real-life the conversion from chronic migraine (CM) to episodic
migraine (EM), specifically to EM with High-Frequency (HFEM: 8–14 monthly migraine days …

Cerebral blood flow and other predictors of responsiveness to erenumab and fremanezumab in migraine—a real-life study

M Nowaczewska, M Straburzyński… - Frontiers in …, 2022 - frontiersin.org
Introduction Monoclonal antibodies (mAbs) showed efficacy in migraine prevention. The aim
of this study was to check if baseline clinical parameters and cerebral blood flow (CBF) …